The interface of condensates of the hnRNPA1 low-complexity domain promotes formation of amyloid fibrils

Miriam Linsenmeier, Lenka Faltova, Chiara Morelli, +7

Nature Chemistry

Hnrnpa1 Low-complexity DomainProtein AssemblyMolecular BiologyCytoskeletonProtein Phase Separation +16

Limited role of free TDP-43 as a diagnostic tool in neurodegenerative diseases

Emily Feneberg, Petra Steinacker, Stefan Lehnert, +6

Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration

Brain Urea FractionsNeurochemical BiomarkersSocial SciencesAlzheimer's DiseaseNeurobiology Of Disease +16

Dynamic arrest and aging of biomolecular condensates are modulated by low-complexity domains, RNA and biochemical activity

Miriam Linsenmeier, Maria Hondele, Fulvio Grigolato, +3

Nature Communications

Dynamics of Synthetic Membraneless Organelles in Microfluidic Droplets

Miriam Linsenmeier, Marie R. G. Kopp, Fulvio Grigolato, +7

Angewandte Chemie International Edition

Sequestration within biomolecular condensates inhibits Aβ-42 amyloid formation

Andreas M. Küffner, Miriam Linsenmeier, Fulvio Grigolato, +5

Chemical Science

Pat1 promotes processing body assembly by enhancing the phase separation of the DEAD-box ATPase Dhh1 and RNA

Ruchika Sachdev, Maria Hondele, Miriam Linsenmeier, +4

eLife

Microfluidic Shrinking Droplet Concentrator for Analyte Detection and Phase Separation of Protein Solutions

Marie R. G. Kopp, Miriam Linsenmeier, Britta Hettich, +4

Analytical Chemistry

Programmable Zwitterionic Droplets as Biomolecular Sorters and Model of Membraneless Organelles

Umberto Capasso Palmiero, Carolina Paganini, Marie R. G. Kopp, +3

Advanced Materials

Biophysical ModelingEngineeringResponsive PolymersMembraneless OrganellesBiomolecular Sorters +17

The interface of condensates of the hnRNPA1 low complexity domain promotes formation of amyloid fibrils

Miriam Linsenmeier, Lenka Faltova, Umberto Capasso Palmiero, +6

Protein AssemblyMolecular BiologyNeurochemical BiomarkersProtein Phase SeparationAlzheimer's Disease +15

Dynamics of Synthetic Membraneless Organelles in Microfluidic Droplets

Miriam Linsenmeier, Marie R. G. Kopp, Fulvio Grigolato, +7

Angewandte Chemie

Molecular BiologyMembraneless OrganellesCytoskeletonCell BiophysicsProtein Phase Separation +15