Keith J. Chappell

Neutralizing antibodies against the preactive form of respiratory syncytial virus fusion protein offer unique possibilities for clinical intervention

Margarita Magro, Vicente Más, Keith J. Chappell et al. · Proceedings of the National Academy of Sciences · 2012 · 265 citations · Full text

Respiratory Virus Immunity, Immunology, Viral Pathogenesis +19

Systems serology detects functionally distinct coronavirus antibody features in children and elderly

Kevin J. Selva, Carolien E. van de Sandt, Melissa M. Lemke et al. · Nature Communications · 2021 · 172 citations · Full text

SARS-CoV-2 drives NLRP3 inflammasome activation in human microglia through spike protein

Eduardo A. Albornoz, Alberto A. Amarilla, Naphak Modhiran et al. · Molecular Psychiatry · 2022 · 164 citations · Full text

Structure of West Nile Virus NS3 Protease: Ligand Stabilization of the Catalytic Conformation

Gautier Robin, Keith J. Chappell, Martin J. Stoermer et al. · Journal of Molecular Biology · 2008 · 146 citations

Virus Structure, Molecular Virology, Biochemistry +9

Safety and immunogenicity of an MF59-adjuvanted spike glycoprotein-clamp vaccine for SARS-CoV-2: a randomised, double-blind, placebo-controlled, phase 1 trial

Keith J. Chappell, Francesca L. Mordant, Zheyi Li et al. · The Lancet Infectious Diseases · 2021 · 117 citations · Full text

Vaccination, Vaccine Safety, Vaccine Development +4