OX40 costimulation turns off Foxp3+ Tregs

Minh Diem Vu, Xiang Xiao, Wenda Gao, +5

Blood

Patients with drug-free long-term graft function display increased numbers of peripheral B cells with a memory and inhibitory phenotype

Annaïck Pallier, Sophie Hillion, Richard Danger, +14

Kidney International

Regenerative MedicineCell TherapyTransplantationStem Cell TransplantationImmunology +8

Curative and β cell regenerative effects of α1-antitrypsin treatment in autoimmune diabetic NOD mice

Maria Koulmanda, Manoj Bhasin, Lauren Hoffman, +10

Proceedings of the National Academy of Sciences

α1-Antitrypsin TreatmentImmunologyRegenerative EffectsImmunotherapyInsulin Signaling +17

Reciprocal generation of Th1/Th17 and T_reg cells by B1 and B2 B cells

Xuemei Zhong, Wenda Gao, Nicolas Degauque, +6

European Journal of Immunology

Adaptive Immune SystemT-regulatory CellImmunologyImmune RegulationImmunotherapy +15

Tolerant Kidney Transplant Patients Produce B Cells with Regulatory Properties

Mélanie Chesneau, Laure Michel, Emilie Dugast, +12

Journal of the American Society of Nephrology

Cell TherapyT-regulatory CellImmunologyImmunotherapyTolerant Kidney Grafts +14

Unique B Cell Differentiation Profile in Tolerant Kidney Transplant Patients

Mélanie Chesneau, Annaïck Pallier, Faouzi Braza, +14

American Journal of Transplantation

UrologyTransplantationKidney TransplantKidney TransplantationImmunology +6

Cytotoxic CD8 ⁺ T lymphocytes expressing ALS-causing SOD1 mutant selectively trigger death of spinal motoneurons

Emmanuelle Coque, Céline Salsac, Gabriel Espinosa-Carrasco, +18

Proceedings of the National Academy of Sciences

The Innate NK Cells, Allograft Rejection, and a Key Role for IL-15

Alexander Kroemer, Xiang Xiao, Nicolas Degauque, +3

The Journal of Immunology

New differentiation pathway for double-negative regulatory T cells that regulates the magnitude of immune responses

Dong Zhang, Wei Yang, Nicolas Degauque, +3

Blood

Immunostimulatory Tim-1–specific antibody deprograms Tregs and prevents transplant tolerance in mice

Nicolas Degauque, Christophe Mariat, James J. Kenny, +10

Journal of Clinical Investigation