The hen’s egg chorioallantoic membrane (HET-CAM) test to predict the ophthalmic irritation potential of a cysteamine-containing gel: Quantification using Photoshop® and ImageJ

Barbara McKenzie, Graeme Kay, Kerr H. Matthews, +2

International Journal of Pharmaceutics

OphthalmologyExperimental OphthalmologyCysteamine-containing GelMedicineToxicology +5

Synthesis of novel vanillin derivatives: novel multi-targeted scaffold ligands against Alzheimer's disease

Matteo Scipioni, Graeme Kay, Ian L. Megson, +1

MedChemComm

Novel vanillin derivatives: Synthesis, anti-oxidant, DNA and cellular protection properties

Matteo Scipioni, Graeme Kay, Ian L. Megson, +1

European Journal of Medicinal Chemistry

Bioorganic ChemistryDerivativesBiochemistryNatural SciencesMedicine +5

Gel formulations for treatment of the ophthalmic complications in cystinosis

Barbara Buchan, Graeme Kay, Anne Heneghan, +2

International Journal of Pharmaceutics

Gel FormulationsOphthalmologyTopical DrugSurgeryGlaucoma +3

Supramolecular structures of six adenine-carboxylic acid complexes

Maureen Byres, Philip Cox, Graeme Kay, +1

CrystEngComm

Nucleic Acid ChemistryDna BindingEngineeringBiochemistryBenzoic Acid +10

Synthesis and in vitro evaluation of vanillin derivatives as multi-target therapeutics for the treatment of Alzheimer’s disease

Laura Blaikie, Graeme Kay, Paul Kong Thoo Lin

Bioorganic & Medicinal Chemistry Letters

Medicinal ChemistryNeurodegenerative DiseasesDerivativesAlzheimer's DiseaseDerivative (Chemistry) +10

A potential new prodrug for the treatment of cystinosis: Design, synthesis and in-vitro evaluation

Bridgeen McCaughan, Graeme Kay, Rachel M. Knott, +1

Bioorganic & Medicinal Chemistry Letters

Medicinal ChemistryUrologyPharmaceutical SciencePotential New ProdrugMedicine +6

Preformulation of cysteamine gels for treatment of the ophthalmic complications in cystinosis

Barbara McKenzie, Graeme Kay, Kerr H. Matthews, +2

International Journal of Pharmaceutics

OphthalmologyExperimental OphthalmologyTopical DrugCysteamine GelsSurgery +5

Experimental modelling of Alzheimer's disease for therapeutic screening

Laura Blaikie, Graeme Kay, Patrı́cia Maciel, +1

European Journal of Medicinal Chemistry Reports

Folate pro-drug of cystamine as an enhanced treatment for nephropathic cystinosis

Ziad Omran, Graeme Kay, Emma E. Hector, +2

Bioorganic & Medicinal Chemistry Letters

UrologyNephropathic CystinosisMedicinePharmacologyFolate Pro-drug +3