Bone marrow mesenchymal stem cells inhibit the response of naive and memory antigen-specific T cells to their cognate peptide

Mauro Krampera, Sarah J. Glennie, Julian Dyson, +4

Blood

Prevention of insulin-dependent diabetes mellitus in non-obese diabetic mice by transgenes encoding modified I-A β-chain or normal I-E α-chain

Torben Lund, Lorraine A. O’Reilly, Patricia Hutchings, +9

Nature

ObesityMetabolic SyndromeNormal I-e α-ChainBiochemistryNon-obese Diabetic Mice +12

Subcellular localization of proteasomes and their regulatory complexes in mammalian cells

Paul Brooks, Graciela Fuertes, Rachael Z. Murray, +7

Biochemical Journal

Different SubunitsSubcellular LocalizationMolecular BiologyProteasomeCytoskeleton +15

PARP14 promotes the Warburg effect in hepatocellular carcinoma by inhibiting JNK1-dependent PKM2 phosphorylation and activation

Valeria Iansante, Pui Man Choy, Sze Wai Fung, +10

Nature Communications

Depletion of regulatory T cells by anti-GITR mAb as a novel mechanism for cancer immunotherapy

David Coe, Shaima Begom, Caroline Addey, +3

Cancer Immunology Immunotherapy

Cancer ImmunosurveillanceMedicineT-regulatory CellImmunologyPathology +8

Anergic T Cells Inhibit the Antigen-Presenting Function of Dendritic Cells

Silvia Vendetti, Jian‐Guo Chai, Julian Dyson, +3

The Journal of Immunology

T-regulatory CellImmunologyT CellsImmunotherapyInflammation +15

Regulatory T Cells, Derived from Naïve CD4+CD25− T Cells by In Vitro Foxp3 Gene Transfer, Can Induce Transplantation Tolerance

Jian‐Guo Chai, Shao‐An Xue, David Coe, +8

Transplantation

Anergic T cells act as suppressor cellsin vitro andin vivo

Jian-Guo Chai, I Bartók, Phillip Chandler, +4

European Journal of Immunology

Fc-dependent depletion of activated T cells occurs through CD40L-specific antibody rather than costimulation blockade

Nicola J. Monk, Roseanna Hargreaves, James E. Marsh, +6

Nature Medicine

Activated T CellsAutoimmune DiseaseCostimulation BlockadeImmunologyAntigen Processing +9

Analysis of the T-Cell Receptor Repertoires of Tumor-Infiltrating Conventional and Regulatory T Cells Reveals No Evidence for Conversion in Carcinogen-Induced Tumors

James P. Hindley, Cristina Ferreira, Emma Jones, +9

Cancer Research

Tcr RepertoiresT-regulatory CellUnique Tcr RepertoiresImmunologyImmunoediting +14