Progranulin induces immune escape in breast cancer via up-regulating PD-L1 expression on tumor-associated macrophages (TAMs) and promoting CD8+ T cell exclusion

Wenli Fang, Ting Zhou, He Shi, +8

Journal of Experimental & Clinical Cancer Research

The miR-186-3p/EREG axis orchestrates tamoxifen resistance and aerobic glycolysis in breast cancer cells

Mengjia He, Qianni Jin, Cong Chen, +9

Oncogene

Breast OncologyTamoxifen ResistanceMedicineBreast Cancer CellsMir-186-3p/ereg Axis +10

Surface plasmon resonance biosensor using hydrogel-AuNP supramolecular spheres for determination of prostate cancer-derived exosomes

Wenqin Chen, Jia Li, Xiaotong Wei, +5

Microchimica Acta

NanomedicineProstate Cancer-derived ExosomesEngineeringNanobiotechnologyBiomedical Analysis +4

Fiber optic surface plasmon resonance biosensor for detection of PDGF-BB in serum based on self-assembled aptamer and antifouling peptide monolayer

Husun Qian, Yu Huang, Xiaolei Duan, +6

Biosensors and Bioelectronics

EngineeringPeptide MonolayerBiosensing SystemsBiomedical DiagnosticsBiomedical Engineering +4

Exosomal miR-100-5p inhibits osteogenesis of hBMSCs and angiogenesis of HUVECs by suppressing the BMPR2/Smad1/5/9 signalling pathway

Yang Wu, Weiwen Zhu, Yunfei Yang, +9

Stem Cell Research & Therapy

PGRN−/− TAMs-derived exosomes inhibit breast cancer cell invasion and migration and its mechanism exploration

Shujun Yue, Xiangsen Ye, Ting Zhou, +7

Life Sciences

ExosomesPgrn−/− Tams-derivedMechanism ExplorationExtracellular MicrovesiclesBreast Cancer +5

Dual-aptamer-engineered M1 macrophage with enhanced specific targeting and checkpoint blocking for solid-tumor immunotherapy

Husun Qian, Yixin Fu, Minkang Guo, +10

Molecular Therapy

Proximity ligation assay mediated rolling circle amplification strategy for in situ amplified imaging of glycosylated PD-L1

Yixin Fu, Husun Qian, Xi Zhou, +7

Analytical and Bioanalytical Chemistry

Proximity LigationBiochemistryNovel Imaging MethodNatural SciencesBioanalysis +9

Self-assembled tetrahedral framework nucleic acid mediates tumor-associated macrophage reprogramming and restores antitumor immunity

Husun Qian, Ting Zhou, Yixin Fu, +10

Molecular Therapy — Nucleic Acids

Cancer ImmunosurveillanceImmunologyTumor ImmunityTumor-associated Macrophage ReprogrammingAntitumor Immunity +7

The miR-345-3p/PPP2CA signaling axis promotes proliferation and invasion of breast cancer cells

Qian Zeng, Fangfang Jin, Husun Qian, +7

Carcinogenesis