Yong Chen

Differentiation and Transplantation of Human Embryonic Stem Cell–Derived Hepatocytes

Hesham Basma, Alejandro Soto–Gutiérrez, Govardhana Rao Yannam et al. · Gastroenterology · 2008 · 514 citations · Full text

Regenerative Medicine, Developmental Biology, Medicine +8

High fat diet produces brain insulin resistance, synaptodendritic abnormalities and altered behavior in mice

Steven E. Arnold, Irwin Lucki, Bethany R. Brookshire et al. · Neurobiology of Disease · 2014 · 301 citations · Full text

Obesity, Metabolic Syndrome, Nutrition +13

Reversal of mouse hepatic failure using an implanted liver-assist device containing ES cell–derived hepatocytes

Alejandro Soto–Gutiérrez, Naoya Kobayashi, Jorge David Rivas‐Carrillo et al. · Nature Biotechnology · 2006 · 218 citations

Regenerative Medicine, Implanted Liver-assist Device, Hepatology +11

A sequential EMT-MET mechanism drives the differentiation of human embryonic stem cells towards hepatocytes

Qiuhong Li, Andrew P. Hutchins, Yong Chen et al. · Nature Communications · 2017 · 139 citations · Full text

A human β-cell line for transplantation therapy to control type 1 diabetes

Michiki Narushima, Naoya Kobayashi, Teru Okitsu et al. · Nature Biotechnology · 2005 · 134 citations

Type 1, Islet Transplantation, Cell Therapy +8