Ikumi Washio

CSAHi study: Evaluation of multi-electrode array in combination with human iPS cell-derived cardiomyocytes to predict drug-induced QT prolongation and arrhythmia — Effects of 7 reference compounds at 10 facilities

Takashi Kitaguchi, Yuta Moriyama, Tomohiko Taniguchi et al. · Journal of Pharmacological and Toxicological Methods · 2015 · 93 citations

Medicine, Cardiology, Pharmacology +17

Cigarette Smoke Extract Induces CYP2B6 through Constitutive Androstane Receptor in Hepatocytes

Ikumi Washio, Makiko Maeda, Chika Sugiura et al. · Drug Metabolism and Disposition · 2010 · 46 citations

Medicine, Pharmacology, Toxicology +16

CSAHi study: Validation of multi-electrode array systems (MEA60/2100) for prediction of drug-induced proarrhythmia using human iPS cell-derived cardiomyocytes -assessment of inter-facility and cells lot-to-lot-variability-

Yumiko Nozaki, Yayoi Honda, Hitoshi Watanabe et al. · Regulatory Toxicology and Pharmacology · 2016 · 37 citations

Medicine, Biomedical Engineering, Cardiology +16

Impact of Experimental Conditions on the Evaluation of Interactions between Multidrug and Toxin Extrusion Proteins and Candidate Drugs

Christian Lechner, Naoki Ishiguro, Hidetada Shimizu et al. · Drug Metabolism and Disposition · 2016 · 26 citations

Medicine, Pharmacokinetics, Pharmacology +17

Usefulness of kidney slices for functional analysis of apical reabsorptive transporters

Hiroshi Arakawa, Ikumi Washio, Natsumi Matsuoka‐Uchiyama et al. · Scientific Reports · 2017 · 15 citations · Full text

Pharmacy, Biochemistry, Pharmacology +16