Melissa Hadley

Selective HDAC6 inhibitors improve anti-PD-1 immune checkpoint blockade therapy by decreasing the anti-inflammatory phenotype of macrophages and down-regulation of immunosuppressive proteins in tumor cells

Tessa Knox, Eva Sahakian, Debarati Banik et al. · Scientific Reports · 2019 · 162 citations · Full text

Medicine, Oncology, Pharmacology +17

Combining DNMT and HDAC6 inhibitors increases anti-tumor immune signaling and decreases tumor burden in ovarian cancer

Sara Moufarrij, Aneil Srivastava, Stephanie Gomez et al. · Scientific Reports · 2020 · 114 citations · Full text

Medicine, Immunology, Oncology +17

Discovery of a New Isoxazole-3-hydroxamate-Based Histone Deacetylase 6 Inhibitor SS-208 with Antitumor Activity in Syngeneic Melanoma Mouse Models

Sida Shen, Melissa Hadley, Kseniya Ustinova et al. · Journal of Medicinal Chemistry · 2019 · 82 citations · Full text

Pharmacy, Medicinal Chemistry, Oncology +16

Exposure to Mission Relevant Doses of 1 GeV/Nucleon⁵⁶Fe Particles Leads to Impairment of Attentional Set-Shifting Performance in Socially Mature Rats

Richard A. Britten, Leslie K. Davis, Jessica S. Jewell et al. · Radiation Research · 2014 · 78 citations · Full text

Medicine, Neuroscience, Psychology +14

HDAC6 Plays a Noncanonical Role in the Regulation of Antitumor Immune Responses, Dissemination, and Invasiveness of Breast Cancer

Debarati Banik, Satish Noonepalle, Melissa Hadley et al. · Cancer Research · 2020 · 68 citations · Full text

Medicine, Oncology, Pharmacology +17