George F. Huhn

Acid-catalyzed nitronate cycloaddition reactions. Useful syntheses and simple transformations of 3-acyl- and 3-alkenylisoxazolines

Peter A. Wade, Nayan V. Amin, Hwa Kwo Yen et al. · The Journal of Organic Chemistry · 1984 · 61 citations

Engineering, Heterocyclic, Donut Icon +11

Practical synthesis and regioselective alkylation of methyl 4(5)-(pentafluoroethyl)-2-propylimidazole-5(4)-carboxylate to give DuP 532, a potent angiotensin II antagonist

Michael E. Pierce, David J. Carini, George F. Huhn et al. · The Journal of Organic Chemistry · 1993 · 48 citations

Medicinal Chemistry, Dup 532, Engineering +12

A Large Scale Preparation of the Cognitive Enhancer Linopirdine

Walter M. Bryant, George F. Huhn, James H. Jensen et al. · Synthetic Communications · 1993 · 23 citations

Medicinal Chemistry, Abstract Linopirdine, Medicine +13

Efficient Pyridinylmethyl Functionalization:  Synthesis of 10,10-Bis[(2-fluoro-4-pyridinyl)methyl]-9(10<i>H</i>)-anthracenone (DMP 543), an Acetylcholine Release Enhancing Agent

Jaan A. Pesti, George F. Huhn, Jianguo Yin et al. · The Journal of Organic Chemistry · 2000 · 10 citations

Efficient Pyridinylmethyl Functionalization, Medicinal Chemistry, Large Scale Synthesis +14