Concepedia

Leeanne McGurk

LM

14

Publications

1.6K

Citations

14

H-Index

2007

Active since

Affiliations

University of Pennsylvania(Current)

Institute of Genetics and Cancer

Western General Hospital

University of Dundee

Stanford University

Leeanne McGurk is an author at University of Pennsylvania specializing in medicine, cell biology, and neurodegenerative diseases.

Top concepts

MedicineCell BiologyNeurodegenerative DiseasesNatural SciencesMolecular BiologyCell SignalingGene ExpressionSynaptic SignalingMolecular SignalingGenetics

Publications per year

2007–2022

14

Publications

14

Poly(ADP-Ribose) Prevents Pathological Phase Separation of TDP-43 by Promoting Liquid Demixing and Stress Granule Localization

Leeanne McGurk, Edward Gomes, Lin Guo et al. · Molecular Cell · 2018 · 410 citations · Full text

Engineering, Polymer Science, Stress Granule Localization +6

Therapeutic modulation of eIF2α phosphorylation rescues TDP-43 toxicity in amyotrophic lateral sclerosis disease models

Hyung‐Jun Kim, Alya R. Raphael, Eva LaDow et al. · Nature Genetics · 2013 · 377 citations · Full text

Neurodegenerative Diseases, Amyotrophic Lateral Sclerosis, Signal Transduction +10

Editing independent effects of ADARs on the miRNA/siRNA pathways

Bret S.E. Heale, Liam P. Keegan, Leeanne McGurk et al. · The EMBO Journal · 2009 · 182 citations · Full text

Systems Biology, Microrna Detection, Cell Biology +6

Nuclear poly(ADP-ribose) activity is a therapeutic target in amyotrophic lateral sclerosis

Leeanne McGurk, Jelena Mojsilovic‐Petrovic, Vivianna M. Van Deerlin et al. · Acta Neuropathologica Communications · 2018 · 114 citations · Full text

Adar RNA editing-dependent and -independent effects are required for brain and innate immune functions in Drosophila

Patricia Deng, Anzer Khan, Dionna Jacobson et al. · Nature Communications · 2020 · 99 citations · Full text

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