Lohman Ph

cis-Diamminedichloroplatinum(II)-induced DNA adducts in peripheral leukocytes from seven cancer patients: quantitative immunochemical detection of the adduct induction and removal after a single dose of cis-diamminedichloroplatinum(II).

Fichtinger-Schepman Am, van Oosterom At, Lohman Ph et al. · PubMed · 1987 · 265 citations

Immunology, Dna Analysis, Pathology +22

Induction and repair of DNA cross-links in chinese hamster ovary cells treated with various platinum coordination compounds in relation to platinum binding to DNA, cytotoxicity, mutagenicity, and antitumor activity.

Plooy Ac, van Dijk M, Lohman Ph · PubMed · 1984 · 169 citations

Chromatin, Genome Instability, Oncology +15

Formation and repair of DNA interstrand cross-links in relation to cytotoxicity and unscheduled DNA synthesis induced in control and mutant human cells treated with cis-diamminedichloroplatinum(II).

Plooy Ac, van Dijk M, Frits J. Berends et al. · PubMed · 1985 · 108 citations

Dna Damage, Molecular Biology, Cell Death +21

Methods of monitoring human exposure to carcinogenic and mutagenic agents.

Lohman Ph, Robert Lauwerys, Marja Sorsa · PubMed · 1984 · 14 citations

Medicine, Environmental Health, Pathology +11