Interaction of poliovirus polypeptide 3CDpro with the 5‘ and 3‘ termini of the poliovirus genome. Identification of viral and cellular cofactors needed for efficient binding.

K S Harris, Wenkai Xiang, Louis Alexander, +3

Journal of Biological Chemistry

Viral ReplicationViral Polymerase StructureViral Polymerase MechanismMolecular BiologyPoliovirus Genome +15

Interaction between the 5'-terminal cloverleaf and 3AB/3CDpro of poliovirus is essential for RNA replication

Wenkai Xiang, K S Harris, Louis Alexander, +1

Journal of Virology

Viral ReplicationRna ReplicationHrv14 HomologMolecular BiologyViral Structural Protein +15

Properties of purified recombinant poliovirus protein 3aB as substrate for viral proteinases and as co-factor for RNA polymerase 3Dpol.

Juan Lama, Aniko V. Paul, K S Harris, +1

Journal of Biological Chemistry

Virus StructureViral ReplicationViral Polymerase StructurePoliovirus-specific Polypeptide 3AbViral Polymerase Mechanism +11

Purification and characterization of poliovirus polypeptide 3CD, a proteinase and a precursor for RNA polymerase

K S Harris, Sesha Reddigari, Martin J.H. Nicklin, +2

Journal of Virology

Virus StructureViral ReplicationProtein FoldingPathogenesisRna Polymerase +13

Poliovirus proteinase 3C: large-scale expression, purification, and specific cleavage activity on natural and synthetic substrates in vitro

Martin J.H. Nicklin, K S Harris, Peter V. Pallai, +1

Journal of Virology

Viral ReplicationSynthetic VirologySynthetic SubstratesMolecular BiologyViral Structural Protein +16

Cleavage of synthetic peptides by purified poliovirus 3C proteinase

Peter V. Pallai, F Burkhardt, M. T. SKOOG, +8

Journal of Biological Chemistry

Cell-based Vaccine ProductionVirus StructureViral ReplicationMolecular VirologyBiochemistry +13

Stimulation of poliovirus proteinase 3Cpro-related proteolysis by the genome-linked protein VPg and its precursor 3AB.

Akhteruzzaman Molla, K S Harris, Aniko V. Paul, +3

Journal of Biological Chemistry

Viral ReplicationViral Polymerase StructureSynthetic VirologyViral Polymerase MechanismImmunology +16

Studies with poliovirus polymerase 3Dpol. Stimulation of poly(U) synthesis in vitro by purified poliovirus protein 3AB.

Aniko V. Paul, Xia Cao, K S Harris, +2

Journal of Biological Chemistry

Viral ReplicationEngineeringViral Polymerase StructureSynthetic VirologyViral Polymerase Mechanism +14

Inhibition of basal transcription by poliovirus: a virus- encoded protease (3Cpro) inhibits formation of TBP-TATA box complex in vitro

Priyanka Yalamanchili, K S Harris, Eckard Wimmer, +1

Journal of Virology

Basal TranscriptionTranscriptional RegulationTbp-tata Box ComplexMolecular VirologyViral Replication +12