Concepedia

Larry W. Hardy

LW

26

Publications

2K

Citations

20

H-Index

1984

Active since

Affiliations

University of Massachusetts Chan Medical School(Current)

Sunovion (United States)

Vion Pharmaceuticals (United States)

Harvard University

University of California, San Francisco

Larry W. Hardy is an author at University of Massachusetts Chan Medical School specializing in medicine, natural sciences, and biochemistry.

ORCID

Top concepts

Publications per year

1984–2022

26

Publications

26

Atomic Structure of Thymidylate Synthase: Target for Rational Drug Design

Larry W. Hardy, Janet Finer-Moore, W.R. Montfort et al. · Science · 1987 · 331 citations

Structure, multiple site binding, and segmental accommodation in thymidylate synthase on binding dUMP and an anti-folate

W.R. Montfort, Kathy M. Perry, Eric B. Fauman et al. · Biochemistry · 1990 · 230 citations

PTR1: a reductase mediating salvage of oxidized pteridines and methotrexate resistance in the protozoan parasite Leishmania major.

Alexandre Ribeiro Bello, Bakela Nare, D. Freedman et al. · Proceedings of the National Academy of Sciences · 1994 · 192 citations · Full text

, , +16

The Roles of Pteridine Reductase 1 and Dihydrofolate Reductase-Thymidylate Synthase in Pteridine Metabolism in the Protozoan Parasite Leishmania major

Bakela Nare, Larry W. Hardy, Stephen M. Beverley · Journal of Biological Chemistry · 1997 · 184 citations · Full text

, , +13

Purification, structure, and properties of Escherichia coli tRNA pseudouridine synthase I.

Harold O. Kammen, Christopher C. Marvel, Larry W. Hardy et al. · Journal of Biological Chemistry · 1988 · 138 citations · Full text

, , +14

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