eIF4A2 drives repression of translation at initiation by Ccr4-Not through purine-rich motifs in the 5′UTR

Ania Wilczynska, Sarah L. Gillen, Tobias Schmidt, +12

Genome biology

Homogeneous Dual-Parametric-Coupled Assay for Simultaneous Nucleotide Exchange and KRAS/RAF-RBD Interaction Monitoring

Kari Kopra, Emmiliisa Vuorinen, Maria Abreu Blanco, +6

Analytical Chemistry

Specific cancer-associated mutations in the switch III region of Ras increase tumorigenicity by nanocluster augmentation

Maja Šolman, Alessio Ligabue, Olga Blaževitš, +10

eLife

Tumor BiologySwitch Iii RegionNanocluster AugmentationIncrease Ras ActivitySpecific Cancer-associated Mutations +12

Fluorescence-Based Protein Stability Monitoring—A Review

Negin Gooran, Kari Kopra

International Journal of Molecular Sciences

Protein AssemblyThermal Shift AssaysProtein RefoldingProtein FoldingBioanalysis +14

Non-competitive aptamer-based quenching resonance energy transfer assay for homogeneous growth factor quantification

Kari Kopra, Markku Syrjänpää, Pekka Hänninen, +1

The Analyst

A homogeneous quenching resonance energy transfer assay for the kinetic analysis of the GTPase nucleotide exchange reaction

Kari Kopra, Alessio Ligabue, Qi Wang, +7

Analytical and Bioanalytical Chemistry

BiochemistryG Protein-coupled ReceptorNatural SciencesOligonucleotideMolecular Biology +4

Sensitive Label-Free Thermal Stability Assay for Protein Denaturation and Protein–Ligand Interaction Studies

Emmiliisa Vuorinen, Salla Valtonen, Ville Eskonen, +4

Analytical Chemistry

Thermal Shift Assay for Small GTPase Stability Screening: Evaluation and Suitability

Kari Kopra, Salla Valtonen, Randa Mahran, +8

International Journal of Molecular Sciences

Thermal Unfolding MethodsProtein AssemblyProtein RefoldingProtein FoldingBioanalysis +16

Nanomolar Protein–Protein Interaction Monitoring with a Label-Free Protein-Probe Technique

Salla Valtonen, Emmiliisa Vuorinen, Taru Kariniemi, +5

Analytical Chemistry

High-Throughput Dual Screening Method for Ras Activities and Inhibitors

Kari Kopra, Arjan J. van Adrichem, Outi M. H. Salo‐Ahen, +3

Analytical Chemistry

Ras ActivitiesMedicinal ChemistryGtpase CyclingHit IdentificationDrug Target +11