X-ray analysis of HIV-1 proteinase at 2.7 Å resolution confirms structural homology among retroviral enzymes

Risto Lapatto, T. Blundell, Andrew M. Hemmings, +11

Nature

Virus StructureViral ReplicationBiochemistryRetroviral EnzymesNatural Sciences +10

Oral Administration of a Prodrug of the Influenza Virus Neuraminidase Inhibitor GS 4071 Protects Mice and Ferrets against Influenza Infection

Dirk B. Mendel, Chun Y. Tai, Paul A. Escarpe, +13

Antimicrobial Agents and Chemotherapy

Identification of GS 4104 as an Orally Bioavailable Prodrug of the Influenza Virus Neuraminidase Inhibitor GS 4071

Weixing Li, Paul A. Escarpe, Eugene Eisenberg, +11

Antimicrobial Agents and Chemotherapy

VaccinationMedicineGs 4071Antiviral Drug DevelopmentAntiviral Therapy +9

Development of Novel Cell Surface CD34-Targeted Recombinant Adenoassociated Virus Vectors for Gene Therapy

Qicheng Yang, Michael Mamounas, Gang Yu, +6

Human Gene Therapy

Characterization and mutational analysis of the helicase and NTPase activities of hepatitis C virus full-length NS3 protein.

Andrew D. Wardell, W. Errington, Giuseppe Ciaramella, +2

Journal of General Virology

Viral ReplicationMolecular BiologyNtpase ActivitiesHelicase/ntpase DomainViral Structural Protein +15

Selection of a Novel Anti-Nicotine Vaccine: Influence of Antigen Design on Antibody Function in Mice

David C. Pryde, Lyn H. Jones, David Gervais, +17

PLoS ONE

Novel Anti-nicotine VaccineImmunologyImmunodominanceHapten DesignPharmacotherapy +21

Antiviral activity of human immunodeficiency virus type 1 protease inhibitors in a single cycle of infection: evidence for a role of protease in the early phase

K. Nagy, Matthew R. Young, C. Baboonian, +3

Journal of Virology

Protease InhibitorsSingle CycleHiv-1 ProteaseAntiviral ActivityMedicine +13

Inhibition of CCR5-Dependent HIV-1 Infection by Hairpin Ribozyme Gene Therapy against CC-Chemokine Receptor 5

Yu Feng, Mark C. Leavitt, Richard Tritz, +9

Virology

MedicineHuman RetrovirusImmunologyAntiviral ResponseMolecular Biology +7

Enhancing immunogenicity of a 3′aminomethylnicotine-DT-conjugate anti-nicotine vaccine with CpG adjuvant in mice and non-human primates

Michael J. McCluskie, David C. Pryde, David Gervais, +8

International Immunopharmacology

VaccinationVaccine DevelopmentAllergy3′Aminomethylnicotine-dt-conjugate Anti-nicotine VaccineImmunology +11

Vaccination with Cancer- and HIV Infection-Associated Endogenous Retrotransposable Elements Is Safe and Immunogenic

Jonah B. Sacha, In-Jeong Kim, Lianchun Chen, +38

The Journal of Immunology