SARS-CoV-2 Omicron BA.5: Evolving tropism and evasion of potent humoral responses and resistance to clinical immunotherapeutics relative to viral variants of concern

Anupriya Aggarwal, Anouschka Akerman, Vanessa Milogiannakis, +26

EBioMedicine

Cancer-Associated Fibroblasts in Pancreatic Ductal Adenocarcinoma Determine Response to SLC7A11 Inhibition

George Sharbeen, Joshua A. McCarroll, Anouschka Akerman, +35

Cancer Research

SARS-CoV-2 Omicron: evasion of potent humoral responses and resistance to clinical immunotherapeutics relative to viral variants of concern

Anupriya Aggarwal, Alberto Ospina Stella, Gregory J. Walker, +28

Monoclonal Antibody TherapiesViral DiagnosticsImmunodeficienciesHumoral ResponseViral Pathogenesis +21

Platform for isolation and characterization of SARS-CoV-2 variants enables rapid characterization of Omicron in Australia

Anupriya Aggarwal, Alberto Ospina Stella, Gregory J. Walker, +39

Nature Microbiology

Emergence and antibody evasion of BQ, BA.2.75 and SARS-CoV-2 recombinant sub-lineages in the face of maturing antibody breadth at the population level

Anouschka Akerman, Vanessa Milogiannakis, Tyra Jean, +47

EBioMedicine

Viral EvolutionAntibody BreadthAntibody EvasionHumoral ResponseImmunology +6

COVID‐19 vaccine failure in chronic lymphocytic leukaemia and monoclonal B‐lymphocytosis; humoural and cellular immunity

Yandong Shen, Jane A. Freeman, Juliette Holland, +15

British Journal of Haematology

Clinical ImmunologyHumoral ResponseImmunologyImmunodominanceImmune System +19

Multiple COVID-19 vaccine doses in CLL and MBL improve immune responses with progressive and high seroconversion

Yandong Shen, Jane A. Freeman, Juliette Holland, +15

Blood

Improvement of immune dysregulation in individuals with long COVID at 24-months following SARS-CoV-2 infection

Chansavath Phetsouphanh, Brendan Jacka, Sara Ballouz, +19

Nature Communications

Novel siRNA therapeutics demonstrate multi-variant efficacy against SARS-CoV-2

Ellen Bowden-Reid, Scott Ledger, Yuan Zhang, +10

Antiviral Research

VaccinationViral EvolutionNovel TherapyRna InterferenceViral Pathogenesis +12

High titre neutralizing antibodies in response to SARS–CoV–2 infection require RBD–specific CD4 T cells that include proliferative memory cells

Chansavath Phetsouphanh, Weng Hua Khoo, Katherine Jackson, +25

Frontiers in Immunology