Joseph I. Clark

Improved Survival with Ipilimumab in Patients with Metastatic Melanoma

F. Stephen Hodi, Steven O’Day, David F. McDermott et al. · New England Journal of Medicine · 2010 · 15.2K citations · Full text

Medicine, Clinical Sciences, Oncology +12

Increased Production of Immature Myeloid Cells in Cancer Patients: A Mechanism of Immunosuppression in Cancer

Bond Almand, Joseph I. Clark, Ekaterina Nikitina et al. · The Journal of Immunology · 2001 · 1.3K citations · Full text

Life Sciences, Cell Biology, Immunology +14

Ipilimumab in patients with melanoma and brain metastases: an open-label, phase 2 trial

Kim Margolin, Marc S. Ernstoff, Omid Hamid et al. · The Lancet Oncology · 2012 · 1.1K citations

Medicine, Oncology, Pharmacology +12

Randomized Phase III Trial of High-Dose Interleukin-2 Versus Subcutaneous Interleukin-2 and Interferon in Patients With Metastatic Renal Cell Carcinoma

David F. McDermott, Meredith M. Regan, Joseph I. Clark et al. · Journal of Clinical Oncology · 2004 · 819 citations

Medicine, Oncology, Pharmacotherapy +15

Induction chemotherapy followed by concurrent chemoradiotherapy (sequential chemoradiotherapy) versus concurrent chemoradiotherapy alone in locally advanced head and neck cancer (PARADIGM): a randomised phase 3 trial

Robert I. Haddad, Anne O’Neill, Guilherme Rabinowits et al. · The Lancet Oncology · 2013 · 747 citations

Medicine, Oncology, Radiation Oncology +14