Type I interferon induces necroptosis in macrophages during infection with Salmonella enterica serovar Typhimurium

Nirmal Robinson, Scott McComb, Rebecca Mulligan, +3

Nature Immunology

Host ResponsePathogenesisImmunologyMicrobiologyInfection Control +4

Insights into the function of the WhiB‐like protein of mycobacteriophage TM4 – a transcriptional inhibitor of WhiB2

Jan Rybniker, Angela Nowag, Edeltraud van Gumpel, +4

Molecular Microbiology

Whib‐like ProteinTranscriptional RegulationMycobacteriophage Tm4Whib-like ProteinsNatural Sciences +13

Genome-wide Analyses of Chromatin State in Human Mast Cells Reveal Molecular Drivers and Mediators of Allergic and Inflammatory Diseases

Gökhan Cildir, John Toubia, Kwok Ho Yip, +9

Immunity

ChromatinAllergyChromatin StateChromatin RemodelingEpigenetic Change +10

Type I interferon enhances necroptosis of <i>Salmonella</i> Typhimurium–infected macrophages by impairing antioxidative stress responses

Nina Judith Hos, Raja Ganesan, Saray Gutiérrez, +5

The Journal of Cell Biology

Nucleolar fibrillarin is an evolutionarily conserved regulator of bacterial pathogen resistance

Varnesh Tiku, Chun Kew, Parul Mehrotra, +3

Nature Communications

Cancer cells adapt FAM134B/BiP mediated ER-phagy to survive hypoxic stress

Sandhya Chipurupalli, Raja Ganesan, Giulia Martini, +8

Cell Death and Disease

Dysregulated Lipid Synthesis by Oncogenic IDH1 Mutation Is a Targetable Synthetic Lethal Vulnerability

Danièl Thomas, Manhong Wu, Yusuke Nakauchi, +13

Cancer Discovery

Ceramide-induced integrated stress response overcomes Bcl-2 inhibitor resistance in acute myeloid leukemia

Alexander C. Lewis, Victoria S. Pope, Melinda N. Tea, +23

Blood

Hematological MalignancySphingolipid CeramideOncologyBcl-2 Inhibitor ResistanceMedicine +13

Mycobacterial Phenolic Glycolipid Inhibits Phagosome Maturation and Subverts the Pro‐inflammatory Cytokine Response

Nirmal Robinson, Thomas Kolter, Martina Wolke, +3

Traffic

Microbial PathogensInnate Immune SystemImmune RegulationImmunologyImmune System +17

Pharmacological STING Activation Is a Potential Alternative to Overcome Drug-Resistance in Melanoma

Sandhya Chipurupalli, Raja Ganesan, S. P. Dhanabal, +2

Frontiers in Oncology

Braf InhibitorsSkin CancerMedicinePhotocarcinogenesisMelanoma +12