Intranasal MSC-derived A1-exosomes ease inflammation, and prevent abnormal neurogenesis and memory dysfunction after status epilepticus

Qianfa Long, Dinesh Upadhya, Bharathi Hattiangady, +5

Proceedings of the National Academy of Sciences

Extracellular MicrovesiclesSocial SciencesNeuroinflammationNeuroregenerationAntiepileptic Drug Treatment +16

Predictable chronic mild stress improves mood, hippocampal neurogenesis and memory

Vipan K. Parihar, Bharathi Hattiangady, Ramkumar Kuruba, +2

Molecular Psychiatry

Early Life StressPsychoneuroimmunologyHippocampal NeurogenesisStress HormonePsychiatry +11

Extracellular vesicles from human iPSC‐derived neural stem cells: miRNA and protein signatures, and anti‐inflammatory and neurogenic properties

Raghavendra Upadhya, Leelavathi N. Madhu, Sahithi Attaluri, +9

Journal of Extracellular Vesicles

Mood and Memory Deficits in a Model of Gulf War Illness Are Linked with Reduced Neurogenesis, Partial Neuron Loss, and Mild Inflammation in the Hippocampus

Vipan K. Parihar, Bharathi Hattiangady, Bing Shuai, +1

Neuropsychopharmacology

Memory DeficitsPsychoneuroimmunologyNeuropsychologyPsychiatryBrain Function +12

Resveratrol Prevents Age-Related Memory and Mood Dysfunction with Increased Hippocampal Neurogenesis and Microvasculature and Reduced Glial Activation

Maheedhar Kodali, Vipan K. Parihar, Bharathi Hattiangady, +3

Scientific Reports

Metformin treatment in late middle age improves cognitive function with alleviation of microglial activation and enhancement of autophagy in the hippocampus

Maheedhar Kodali, Sahithi Attaluri, Leelavathi N. Madhu, +5

Aging Cell

Object location and object recognition memory impairments, motivation deficits and depression in a model of Gulf War illness

Bharathi Hattiangady, Vikas Mishra, Maheedhar Kodali, +3

Frontiers in Behavioral Neuroscience

Human induced pluripotent stem cell-derived MGE cell grafting after status epilepticus attenuates chronic epilepsy and comorbidities via synaptic integration

Dinesh Upadhya, Bharathi Hattiangady, Olagide Wagner de Castro, +8

Proceedings of the National Academy of Sciences

Chronic Oxidative Stress, Mitochondrial Dysfunction, Nrf2 Activation and Inflammation in the Hippocampus Accompany Heightened Systemic Inflammation and Oxidative Stress in an Animal Model of Gulf War Illness

Geetha A. Shetty, Bharathi Hattiangady, Dinesh Upadhya, +5

Frontiers in Molecular Neuroscience

Intranasally administered human MSC-derived extracellular vesicles inhibit NLRP3-p38/MAPK signaling after TBI and prevent chronic brain dysfunction

Maheedhar Kodali, Leelavathi N. Madhu, Roxanne L. Reger, +10

Brain Behavior and Immunity

Traumatic Brain InjuryImmunologyCell DeathExtracellular MicrovesiclesNeuroinflammation +19