Generation of Hepatic Stellate Cells from Human Pluripotent Stem Cells Enables In Vitro Modeling of Liver Fibrosis

Mar Coll, Luís Perea, Ruben Boon, +16

Cell stem cell

Tissue EngineeringLiver FibrosisEngineeringHepatic Stellate CellsAdult Stem Cell +14

Novel human hepatic organoid model enables testing of drug-induced liver fibrosis in vitro

Sofia Batista Leite, T. Roosens, Adil El Taghdouini, +6

Biomaterials

Translational MedicineFibrosisHepatologyMedicineLiver Physiology +13

Single-cell RNA sequencing of human liver reveals hepatic stellate cell heterogeneity

Valéry L. Payen, Arnaud Lavergne, Niki Alevra Sarika, +8

JHEP Reports

Amino acid levels determine metabolism and CYP450 function of hepatocytes and hepatoma cell lines

Ruben Boon, Manoj Kumar, Tine Tricot, +25

Nature Communications

In vitro reversion of activated primary human hepatic stellate cells

Adil El Taghdouini, Mustapha Najimi, Pau Sancho‐Bru, +2

Fibrogenesis & Tissue Repair

Integrative miRNA and Gene Expression Profiling Analysis of Human Quiescent Hepatic Stellate Cells

Mar Coll, Adil El Taghdouini, Luís Perea, +14

Scientific Reports

Genome-wide analysis of DNA methylation and gene expression patterns in purified, uncultured human liver cells and activated hepatic stellate cells

Adil El Taghdouini, Anita L. Sørensen, Andrew H. Reiner, +11

Oncotarget

Gene Expression Profiling and Secretome Analysis Differentiate Adult-Derived Human Liver Stem/Progenitor Cells and Human Hepatic Stellate Cells

Silvia Berardis, Catherine Lombard, Jonathan Evraerts, +7

PLoS ONE

Distinct Secretion ProfilesPathologyCholangiopathiesGene Expression ProfilingCirrhosis +21

Influence of inflammation on the immunological profile of adult-derived human liver mesenchymal stromal cells and stellate cells

Gordana Raicevic, Mehdi Najar, Mustapha Najimi, +4

Cytotherapy

InflammationAutoimmune DiseaseHepatologyLiver PhysiologyImmunology +12

Pentraxin‐3 modulates lipopolysaccharide‐induced inflammatory response and attenuates liver injury

Luís Perea, Mar Coll, Lucía Sanjurjo, +13

Hepatology