A Novel TRPM2 Isoform Inhibits Calcium Influx and Susceptibility to Cell Death

Wenyi Zhang, Xin Chu, Qin Tong, +4

Journal of Biological Chemistry

Cell PhysiologyMolecular PhysiologySignal TransductionSignaling PathwayCell Regulation +13

Molecular Fingerprint-Based Artificial Neural Networks QSAR for Ligand Biological Activity Predictions

Kyaw-Zeyar Myint, Lirong Wang, Qin Tong, +1

Molecular Pharmaceutics

Lead CompoundsDrug TargetHit IdentificationMolecular BiologySystems Pharmacology +22

Regulation of the Transient Receptor Potential Channel TRPM2 by the Ca2+ Sensor Calmodulin

Qin Tong, Wenyi Zhang, Kathleen Conrad, +4

Journal of Biological Chemistry

ApoptosisNeurotransmitterCell DeathNeurotransmissionCellular Physiology +21

TRPM2 is an ion channel that modulates hematopoietic cell death through activation of caspases and PARP cleavage

Wenyi Zhang, Iwona Hirschler‐Laszkiewicz, Qin Tong, +8

American Journal of Physiology-Cell Physiology

T-regulatory CellApoptosisImmunologyCell DeathPathology +17

Interaction of TRPC2 and TRPC6 in Erythropoietin Modulation of Calcium Influx

Xin Chu, Qin Tong, Joseph Y. Cheung, +7

Journal of Biological Chemistry

Role of TRPM2 in cell proliferation and susceptibility to oxidative stress

Shu-Jen Chen, Wenyi Zhang, Qin Tong, +6

American Journal of Physiology-Cell Physiology

Lipid PeroxidationCell DeathCell ProliferationCellular PhysiologyTrpm2 Isoform +19

Lead Discovery, Chemistry Optimization, and Biological Evaluation Studies of Novel Biamide Derivatives as CB₂Receptor Inverse Agonists and Osteoclast Inhibitors

Peng Yang, Kyaw-Zeyar Myint, Qin Tong, +13

Journal of Medicinal Chemistry

TRPC3 Is the Erythropoietin-regulated Calcium Channel in Human Erythroid Cells

Qin Tong, Iwona Hirschler‐Laszkiewicz, Wenyi Zhang, +5

Journal of Biological Chemistry

Novel Triaryl Sulfonamide Derivatives as Selective Cannabinoid Receptor 2 Inverse Agonists and Osteoclast Inhibitors: Discovery, Optimization, and Biological Evaluation

Peng Yang, Liping Wang, Rentian Feng, +7

Journal of Medicinal Chemistry

Target-Selective Phototherapy Using a Ligand-Based Photosensitizer for Type 2 Cannabinoid Receptor

Shaojuan Zhang, Ningyang Jia, Pin Shao, +3

Chemistry & Biology