Adam B. Keeton

Sulindac Selectively Inhibits Colon Tumor Cell Growth by Activating the cGMP/PKG Pathway to Suppress Wnt/β-Catenin Signaling

Nan Li, Yaguang Xi, Heather N. Tinsley et al. · Molecular Cancer Therapeutics · 2013 · 133 citations · Full text

Inhibition of PDE5 by Sulindac Sulfide Selectively Induces Apoptosis and Attenuates Oncogenic Wnt/β-Catenin–Mediated Transcription in Human Breast Tumor Cells

Heather N. Tinsley, Bernard D. Gary, Adam B. Keeton et al. · Cancer Prevention Research · 2011 · 111 citations · Full text

Suppression of Wnt/β-catenin signaling inhibits prostate cancer cell proliferation

Wenyan Lü, Heather N. Tinsley, Adam B. Keeton et al. · European Journal of Pharmacology · 2008 · 104 citations · Full text

Urology, Signaling Pathway, Cancer Cell Biology +6

Sulindac sulfide selectively inhibits growth and induces apoptosis of human breast tumor cells by phosphodiesterase 5 inhibition, elevation of cyclic GMP, and activation of protein kinase G

Heather N. Tinsley, Bernard D. Gary, Adam B. Keeton et al. · Molecular Cancer Therapeutics · 2009 · 99 citations · Full text

Cgmp Pde Inhibitors, Breast Oncology, Chemoprevention Strategy +17

A Novel Sulindac Derivative That Does Not Inhibit Cyclooxygenases but Potently Inhibits Colon Tumor Cell Growth and Induces Apoptosis with Antitumor Activity

Gary A. Piazza, Adam B. Keeton, Heather N. Tinsley et al. · Cancer Prevention Research · 2009 · 97 citations · Full text