Ahmed T. Negmeldin

Mutagenesis Studies of the 14 Å Internal Cavity of Histone Deacetylase 1: Insights toward the Acetate-Escape Hypothesis and Selective Inhibitor Design

Magdalene K. Wambua, Dhanusha A. Nalawansha, Ahmed T. Negmeldin et al. · Journal of Medicinal Chemistry · 2014 · 47 citations · Full text

Histone Modifications, Epigenetic Change, å Internal Cavity +21

The structural requirements of histone deacetylase inhibitors: C4-modified SAHA analogs display dual HDAC6/HDAC8 selectivity

Ahmed T. Negmeldin, Joseph R. Knoff, Mary Kay H. Pflum · European Journal of Medicinal Chemistry · 2017 · 46 citations · Full text

Histone Modifications, Drug Target, Biochemistry +11

Structural Requirements of HDAC Inhibitors: SAHA Analogues Modified at the C2 Position Display HDAC6/8 Selectivity

Ahmed T. Negmeldin, Geetha Padige, Anton V. Bieliauskas et al. · ACS Medicinal Chemistry Letters · 2017 · 39 citations · Full text

Molecular docking and statistical optimization of taurocholate-stabilized galactose anchored bilosomes for the enhancement of sofosbuvir absorption and hepatic relative targeting efficiency

Marianne J. Naguib, Amira Moustafa Kamel, Ahmed T. Negmeldin et al. · Drug Delivery · 2020 · 32 citations · Full text

Design, synthesis, and screening of <i>ortho-</i>amino thiophene carboxamide derivatives on hepatocellular carcinomaas VEGFR-2Inhibitors

Mohammed K. Abdelhameid, Madlen B. Labib, Ahmed T. Negmeldin et al. · Journal of Enzyme Inhibition and Medicinal Chemistry · 2018 · 30 citations · Full text