Tadahiko Tsushima

Fluorine containing amino acids and their derivatives. 7. Synthesis and antitumor activity of α- and γ-substituted methotrexate analogs

Tadahiko Tsushima, Kenji Kawada, Shoichi Ishihara et al. · Tetrahedron · 1988 · 117 citations

Medicinal Chemistry, Derivatives, Amino Acids +10

Acylation of olefins by acetyl hexachloroantimonate. Selective formation of .beta.,.gamma.-unsaturated ketones under kinetic control and mechanistic rationale as an ene reaction

H. M. R. Hoffmann, Tadahiko Tsushima · Journal of the American Chemical Society · 1977 · 50 citations

Halogenation, Engineering, Chemical Analysis +13

α-fluorination of ketones by xenon and iodobenzene difluorides: A stereochemical evidence demonstrating their mechanistic differences

Tadahiko Tsushima, Kenji Kawada, Teruji Tsuji · Tetrahedron Letters · 1982 · 44 citations

Chemical Engineering, Mechanistic Differences, Engineering +6

Fluorine-containing amino acids and their derivatives. 6. An efficient synthesis of β-fluorinated alanines via fluorohalomethylation of aminomalonates

Tadahiko Tsushima, Kenji Kawada · Tetrahedron Letters · 1985 · 41 citations

Halogenation, Bioorganic Chemistry, Derivatives +10

.alpha.-Fluorination of ketones. 1. Direct fluorination of pyruvic acid derivatives by using molecular fluorine

Tadahiko Tsushima, Kenji Kawada, Teruji Tsuji et al. · The Journal of Organic Chemistry · 1982 · 39 citations

Halogenation, Pyruvic Acid Derivatives, Chemical Engineering +14