Binding of different dimeric forms of PDGF to human fibroblasts: evidence for two separate receptor types.

C H Heldin, G. Bäckström, Arne Östman, +5

The EMBO Journal

FibrosisMolecular PhysiologyPathologyFibroblast Growth FactorDifferent Dimeric Forms +7

A major part of platelet-derived growth factor purified from human platelets is a heterodimer of one A and one B chain.

Annet Hammacher, Ulf Hellman, A. Johnsson, +5

Journal of Biological Chemistry

A glioma-derived PDGF a chain homodimer has different functional activities from a PDGF AB heterodimer purified from human platelets

Monica Nistér, Annet Hammacher, Karin Mellström, +4

Cell

ThrombopoiesisChain HomodimerGliomaBlood PlateletPdgf Ab Heterodimer +5

Differential effects of the various isoforms of platelet-derived growth factor on chemotaxis of fibroblasts, monocytes, and granulocytes.

Agneta Siegbahn, Annet Hammacher, Bengt Westermark, +1

Journal of Clinical Investigation

Different IsoformsVarious IsoformsImmunologyBlood CellCell Growth +17

High affinity interleukin-6 receptor is a hexameric complex consisting of two molecules each of interleukin-6, interleukin-6 receptor, and gp-130.

L.D. Ward, G.J. Howlett, Gesualda Discolo, +4

Journal of Biological Chemistry

Possible positive autocrine feedback in the prereplicative phase of human fibroblasts

Ylva Paulsson, Annet Hammacher, Carl‐Henrik Heldin, +1

Nature

FibrosisSignal TransductionCell-matrix InteractionFibroblast Growth FactorCytoskeleton +9

Isoform-specific induction of actin reorganization by platelet-derived growth factor suggests that the functionally active receptor is a dimer.

Annet Hammacher, Karin Mellström, Carl‐Henrik Heldin, +1

The EMBO Journal

CytoskeletonCell GrowthCellular PhysiologyActive ReceptorActin Reorganization +14

Identification and Structural Analysis of the A Type Receptor for Platelet-derived Growth Factor

Lena Claesson‐Welsh, Annet Hammacher, Bengt Westermark, +2

Journal of Biological Chemistry

ImmunologyPathologyImmunotherapyGliomaTumor Biology +22

Cultured human endothelial cells express platelet-derived growth factor A chain.

Tucker Collins, J S Pober, M A Gimbrone, +4

PubMed

Aberrant expression of receptors for platelet-derived growth factor in an anaplastic thyroid carcinoma cell line.

N E Heldin, Bengt Gustavsson, Lena Claesson‐Welsh, +4

Proceedings of the National Academy of Sciences

ImmunologyPathologyPdgf ReceptorsTumor BiologyType Pdgf Receptors +15