Mahmoud Elshal

Preventive empagliflozin activity on acute acetic acid-induced ulcerative colitis in rats via modulation of SIRT-1/PI3K/AKT pathway and improving colon barrier

Marwa S. Zaghloul, Mahmoud Elshal, Marwa E. Abdelmageed · Environmental Toxicology and Pharmacology · 2022 · 51 citations

Life Sciences, Pharmacology, Pharmacotherapy +17

Escin suppresses immune cell infiltration and selectively modulates Nrf2/HO-1, TNF-α/JNK, and IL-22/STAT3 signaling pathways in concanavalin A-induced autoimmune hepatitis in mice

Mahmoud Elshal, Sara H. Hazem · Inflammopharmacology · 2022 · 31 citations · Full text

Veterinary Medicine, Immunology, Pharmacology +17

Diacerein counteracts acetaminophen-induced hepatotoxicity in mice via targeting NLRP3/caspase-1/IL-1β and IL-4/MCP-1 signaling pathways

Mahmoud Elshal, Marwa E. Abdelmageed · Archives of Pharmacal Research · 2022 · 27 citations · Full text

Veterinary Medicine, Pharmacology, Toxicology +17

Retinoic acid modulates IL-4, IL-10 and MCP-1 pathways in immune mediated hepatitis and interrupts CD4+ T cells infiltration

Mahmoud Elshal, Nashwa Abu‐Elsaad, Amr El-Karef et al. · International Immunopharmacology · 2019 · 23 citations

Life Sciences, Immunology, Pathology +14

The multi-kinase inhibitor pazopanib targets hepatic stellate cell activation and apoptosis alleviating progression of liver fibrosis

Mahmoud Elshal, Nashwa Abu‐Elsaad, Amr El-Karef et al. · Naunyn-Schmiedeberg s Archives of Pharmacology · 2015 · 21 citations

Medicine, Pathology, Pharmacology +12