A Novel HER3-Targeting Antibody–Drug Conjugate, U3-1402, Exhibits Potent Therapeutic Efficacy through the Delivery of Cytotoxic Payload by Efficient Internalization

Yuuri Hashimoto, Kumiko Koyama, Yasuki Kamai, +20

Clinical Cancer Research

Purification of atrial natriuretic peptide receptor from bovine lung. Evidence for a disulfide-linked subunit structure.

Motoyuki Shimonaka, Toshihiko Saheki, Hiromi Hagiwara, +7

Journal of Biological Chemistry

Molecular PharmacologyMolecular PhysiologyKidney Anp ReceptorBiochemistryDisulfide-linked Subunit Structure +11

Retinol-induced morphological changes of cultured bovine endothelial cells are accompanied by a marked increase in transglutaminase

Keigo Nara, Kohei Nakanishi, Hiromi Hagiwara, +3

Journal of Biological Chemistry

Endothelial CellsRetinoic AcidPathologyCell CultureCell Proliferation +18

Purification and characterization of angiotensin‐binding protein from porcine liver cytosolic fraction

Hiromi Hagiwara, Naoaki Sugiura, Kenichi Wakita, +1

European Journal of Biochemistry

Novel anti-GARP antibody DS-1055a augments anti-tumor immunity by depleting highly suppressive GARP+ regulatory T cells

K. Satoh, Yoichi Kobayashi, Kaori Fujimaki, +21

International Immunology

Fucosterol decreases angiotensin converting enzyme levels with reduction of glucocorticoid receptors in endothelial cells

Hiromi Hagiwara, Kenichi Wakita, Yǔji Inada, +1

Biochemical and Biophysical Research Communications

InflammationVascular DiseaseEndothelial CellsCardiovascular DiseaseMedicine +10

Antitumor bicyclic hexapeptide RA-VII modulates cyclin D1 protein level

Kenichi Wakita, Megumi Minami, Venkateswarlu Akella, +3

Anti-Cancer Drugs

Chemoprevention StrategyOncogenic AgentMedicineImmunologyPharmacology +11

The effect of calcium ionophore A23187 on tissue factor activity and mRNA in endothelial cells

Kenichi Wakita, Deborah J. Stearns-Kurosawa, Yasumasa Marumoto

Thrombosis Research

Endothelial CellsCardiovascular FunctionCellular PhysiologyInflammationAngiogenesis +14

High-level expression of recombinant human soluble thrombomodulin in serum-free medium by CHO-K1 cells

Masaaki Ogata, Kenichi Wakita, Kazuo Kimura, +3

Applied Microbiology and Biotechnology

InflammationThrombosisThrombopoiesisAutoimmune DiseaseBlood Platelet +13

Pan-cancer gene expression analysis of tissue microarray using EdgeSeq oncology biomarker panel and a cross-comparison with HER2 and HER3 immunohistochemical analysis

Koichiro Inaki, Tomoko Shibutani, Naoyuki Maeda, +7

PLoS ONE