Wen Gu

Congenital hyperthyroidism caused by a solitary toxic adenoma harboring a novel somatic mutation (serine281-->isoleucine) in the extracellular domain of the thyrotropin receptor.

Peter Kopp, Sarah Muirhead, N. Jourdain et al. · Journal of Clinical Investigation · 1997 · 129 citations · Full text

Congenital Hyperthyroidism, Somatic Mutations, Thyroid Adenomas +12

The thyrotropin (TSH) receptor transmembrane domain mutation (Pro556-Leu) in the hypothyroid hyt/hyt mouse results in plasma membrane targeting but defective TSH binding.

Wen Gu, G G Du, Peter Kopp et al. · Endocrinology · 1995 · 78 citations

Hyt/hyt Mouse, Immunology, Reporter Gene +17

Nε-carboxymethyl-lysine-induced PI3K/Akt signaling inhibition promotes foam cell apoptosis and atherosclerosis progression

Zhongqun Wang, Zhengyang Bao, Yingpeng Ding et al. · Biomedicine & Pharmacotherapy · 2019 · 35 citations · Full text

Macrophage galectin-3 enhances intimal translocation of vascular calcification in diabetes mellitus

Zhen Sun, Lihua Li, Lili Zhang et al. · American Journal of Physiology-Heart and Circulatory Physiology · 2020 · 30 citations · Full text

The thyrotropin (TSH) receptor transmembrane domain mutation (Pro556- Leu) in the hypothyroid hyt/hyt mouse results in plasma membrane targeting but defective TSH binding

Wen Gu · Endocrinology · 1995 · 28 citations

Hyt/hyt Mouse, Immunology, Reporter Gene +18