NLRP3 inflammasome-mediated pyroptosis contributes to the pathogenesis of non-ischemic dilated cardiomyopathy

Cheng Zeng, Fengqi Duan, Jia Hu, +8

Redox Biology

Hyperhomocysteinemia Decreases Circulating High-Density Lipoprotein by Inhibiting Apolipoprotein A-I Protein Synthesis and Enhancing HDL Cholesterol Clearance

Dan Liao, Hongmei Tan, Rutai Hui, +10

Circulation Research

Apolipoprotein A1HyperlipidemiaOxidative StressInflammationMetabolic Syndrome +14

Hyperhomocystinemia Impairs Endothelial Function and eNOS Activity via PKC Activation

Xiaohua Jiang, Fan Yang, Hongmei Tan, +8

Arteriosclerosis Thrombosis and Vascular Biology

Activation of NLRP3 inflammasomes contributes to hyperhomocysteinemia-aggravated inflammation and atherosclerosis in apoE-deficient mice

Renqing Wang, Yiqin Wang, Nana Mu, +5

Laboratory Investigation

Ghrelin prevents doxorubicin-induced cardiotoxicity through TNF-alpha/NF-κB pathways and mitochondrial protective mechanisms

Zhiwei Xu, Shiqing Lin, Wei-Kang Wu, +5

Toxicology

InflammationMitochondrial Protective MechanismsDoxorubicin-induced CardiotoxicityCardiovascular ToxicityTnf-alpha/nf-κb Pathways +8

Human Gingiva-Derived Mesenchymal Stem Cells Modulate Monocytes/Macrophages and Alleviate Atherosclerosis

Ximei Zhang, Feng Huang, Weixuan Li, +12

Frontiers in Immunology

A comprehensive data mining study shows that most nuclear receptors act as newly proposed homeostasis-associated molecular pattern receptors

Luqiao Wang, Gayani Nanayakkara, Qian Yang, +20

Journal of Hematology & Oncology

Ginsenoside Rb1 Preconditioning Protects Against Myocardial Infarction After Regional Ischemia and Reperfusion by Activation of Phosphatidylinositol-3-kinase Signal Transduction

Zhi Wang, Min Li, Wei-Kang Wu, +2

Cardiovascular Drugs and Therapy

InflammationThrombosisCardiovascular DiseaseAtherosclerosisMedicine +11

Metformin inhibited Nod-like receptor protein 3 inflammasomes activation and suppressed diabetes-accelerated atherosclerosis in apoE−/− mice

Ge Tang, Fengqi Duan, Weixuan Li, +7

Biomedicine & Pharmacotherapy

The combination of Panax ginseng and Angelica sinensis alleviates ischemia brain injury by suppressing NLRP3 inflammasome activation and microglial pyroptosis

Jia Hu, Cheng Zeng, Jie Wei, +4

Phytomedicine