Dissection of the enhancer activity of beta-globin 5' DNase I-hypersensitive site 2 in transgenic mice.

D Liu, Judy C. Chang, Paolo Moi, +3

Proceedings of the National Academy of Sciences

GeneticsGenomic MechanismMolecular BiologyMolecular GeneticsTransgenic Mice +16

Differential recruitment of steroid hormone response elements may dictate the expression of the pituitary gonadotropin II beta subunit gene during salmon maturation.

Fei Xiong, D Liu, Yves Le Dréan, +2

Molecular Endocrinology

SpermatogenesisPituitary CellsGeneticsReproductive BiologyEpigenetics +19

A 36-base-pair core sequence of locus control region enhances retrovirally transferred human beta-globin gene expression.

J. Chang, D Liu, Yuet Wai Kan

Proceedings of the National Academy of Sciences

Transcriptional RegulationViral ReplicationPackaging Cell LinesMedicineGenetics +12

Blocking high-fat diet-induced obesity, insulin resistance and fatty liver by overexpression of Il-13 gene in mice

P Darkhal, Mingming Gao, Yiwen Ma, +1

International Journal of Obesity

InflammationNutritionMetabolic SyndromeObesityIl-13 Gene +11

Overexpression of superoxide dismutase 3 gene blocks high-fat diet-induced obesity, fatty liver and insulin resistance

Ran Cui, Mingming Gao, Shen Qu, +1

Gene Therapy

ObesityInsulin ResistanceMetabolic SyndromeBiochemistryLipid Peroxidation +9

Hydrodynamic delivery of interleukin 15 gene promotes resistance to high fat diet-induced obesity, fatty liver and improves glucose homeostasis

Hao Sun, D Liu

Gene Therapy

ObesityMetabolic SyndromeInflammationMedicineLiver Physiology +8

Interferon beta overexpression attenuates adipose tissue inflammation and high-fat diet-induced obesity and maintains glucose homeostasis

Mohammad Alsaggar, Melanie J. Mills, D Liu

Gene Therapy

InflammationMetabolic SyndromeObesityHigh-fat Diet-induced ObesityInsulin Signaling +11

Novel electric power-driven hydrodynamic injection system for gene delivery: safety and efficacy of human factor IX delivery in rats

Takeshi Yokoo, Kenya Kamimura, Takeshi Suda, +5

Gene Therapy

Regenerative MedicineTissue EngineeringCell-based Drug DeliveryEngineeringMedicine +6

IL-15/sIL-15Rα gene transfer induces weight loss and improves glucose homeostasis in obese mice

Hao Sun, Yiwen Ma, Mingming Gao, +1

Gene Therapy

InflammationMetabolic SyndromeObesityEnergy HomeostasisPhysiology +12

IL-15/sIL-15Rα gene transfer suppresses Lewis lung cancer growth in the lungs, liver and kidneys

Hao Sun, D Liu

Cancer Gene Therapy

Tumor BiologyMedicineImmunologyPathologyTumor Suppressor +5