FOXD1–ALDH1A3 Signaling Is a Determinant for the Self-Renewal and Tumorigenicity of Mesenchymal Glioma Stem Cells

Peng Cheng, Jia Wang, Indrayani Waghmare, +14

Cancer Research

Transcriptional RegulationDevelopmental BiologyFoxd1–aldh1a3 SignalingTherapeutic ResistanceMedicine +12

Imidazo[1,2-<i>a</i>]pyridine Derivatives as Aldehyde Dehydrogenase Inhibitors: Novel Chemotypes to Target Glioblastoma Stem Cells

Luca Quattrini, Edoardo Luigi Maria Gelardi, Vito Coviello, +6

Journal of Medicinal Chemistry

Nanostructured ultra-thin patches for ultrasound-modulated delivery of anti-restenotic drug

Lorenzo Vannozzi, Leonardo Ricotti, Carlo Filippeschi, +7

International Journal of Nanomedicine

Identification of ALDH1A3 as a Viable Therapeutic Target in Breast Cancer Metastasis–Initiating Cells

Daisuke Yamashita, Mutsuko Minata, Ahmed N. Ibrahim, +8

Molecular Cancer Therapeutics

Tumor BiologyBreast OncologyViable Therapeutic TargetGliomaMedicine +13

Cyclodextrin-based nanosponges for the targeted delivery of the anti-restenotic agent DB103: A novel opportunity for the local therapy of vessels wall subjected to percutaneous intervention

Vito Coviello, Stefania Sartini, Luca Quattrini, +3

European Journal of Pharmaceutics and Biopharmaceutics

NanomedicineEngineeringAnti-restenotic Agent Db103Polymer-drug ConjugateTargeted Delivery +8

1,2-Benzisothiazole Derivatives Bearing 4-, 5-, or 6-Alkyl/arylcarboxamide Moieties Inhibit Carbonic Anhydrase Isoform IX (CAIX) and Cell Proliferation under Hypoxic Conditions

Vito Coviello, Beatrice Marchi, Stefania Sartini, +13

Journal of Medicinal Chemistry

Pharmaceutical ScienceBioorganic ChemistryOrganic ChemistryCell ProliferationChemical Derivative +15

Quinazolinone-based rhodanine-3-acetic acids as potent aldose reductase inhibitors: Synthesis, functional evaluation and molecular modeling study

Sherihan El‐Sayed, Kamel Metwally, Abdalla A. El‐Shanawani, +6

Bioorganic & Medicinal Chemistry Letters

Medicinal ChemistryMolecular Modeling StudyFunctional EvaluationAldo-keto ReductaseBiochemistry +9

Acid Derivatives of Pyrazolo[1,5-a]pyrimidine as Aldose Reductase Differential Inhibitors

Francesco Balestri, Luca Quattrini, Vito Coviello, +7

Cell chemical biology

Acid DerivativesMedicinal ChemistryAldo-keto ReductaseBiochemistryMedicine +5

Novel Quinazolinone-Based 2,4-Thiazolidinedione-3-Acetic Acid Derivatives as Potent Aldose Reductase Inhibitors

Kamel Metwally, Harris Pratsinis, Dimitris Kletsas, +5

Future Medicinal Chemistry

Structure-Based Optimization of Tyrosine Kinase Inhibitor <b>CLM3</b>. Design, Synthesis, Functional Evaluation, and Molecular Modeling Studies.

Stefania Sartini, Vito Coviello, Agostino Bruno, +13

Journal of Medicinal Chemistry

Functional EvaluationDrug TargetChemoprevention StrategyStructure-based OptimizationChemical Biology +19