DNA Repair Network Analysis Reveals Shieldin as a Key Regulator of NHEJ and PARP Inhibitor Sensitivity

Rajat Gupta, Kumar Somyajit, Takeo Narita, +9

Cell

ChromatinGenome InstabilityKey RegulatorMolecular TechnologyNatural Sciences +5

Structural and mechanistic insights into the interaction between Rho and mammalian Dia

Rolf Rose, Michael Weyand, Michael Lammers, +3

Nature

Protein FunctionBiochemistryProtein AssemblyNatural SciencesBiophysical Aspect +8

Analysis of human acetylation stoichiometry defines mechanistic constraints on protein regulation

Bogi Karbech Hansen, Rajat Gupta, Linda Baldus, +5

Nature Communications

The regulation of mDia1 by autoinhibition and its release by Rho•GTP

Michael Lammers, Rolf Rose, Andrea Scrima, +1

The EMBO Journal

Molecular PhysiologyBiochemistryMolecular RegulationMedicineNatural Sciences +4

Multiple Substrate Binding Mode-Guided Engineering of a Thermophilic PET Hydrolase

Lara Pfaff, Jian Gao, Zhishuai Li, +16

ACS Catalysis

EngineeringEnzymatic ModificationActive Pet HydrolasePolymersBiochemical Engineering +17

Specificity of Interactions between mDia Isoforms and Rho Proteins

Michael Lammers, Simon F. De Meyer, Dorothee Kühlmann, +1

Journal of Biological Chemistry

Acetylation regulates Cyclophilin A catalysis, immunosuppression and HIV isomerization

Michael Lammers, Heinz Neumann, Jason W. Chin, +1

Nature Chemical Biology

BiochemistryNatural SciencesHuman RetrovirusImmunologyHiv Isomerization +5

Active site remodeling switches HIV specificity of antiretroviral TRIMCyp

Amanda J. Price, Flavia Marzetta, Michael Lammers, +5

Nature Structural & Molecular Biology

Treatment And PreventionHuman RetrovirusActive SiteHivMedicine +1

Structural Insights into (Tere)phthalate-Ester Hydrolysis by a Carboxylesterase and Its Role in Promoting PET Depolymerization

Gerlis von Haugwitz, Xu Han, Lara Pfaff, +17

ACS Catalysis

Acetylation regulates ribonucleotide reductase activity and cancer cell growth

Guo Chen, Yin Luo, Kurt Warncke, +10

Nature Communications