James C. Chen

Microenvironmental reprogramming by three-dimensional culture enables dermal papilla cells to induce de novo human hair-follicle growth

Claire A. Higgins, James C. Chen, Jane Cerise et al. · Proceedings of the National Academy of Sciences · 2013 · 391 citations · Full text

Life Sciences, Cell Biology, Systems Biology +16

Safety and efficacy of the JAK inhibitor tofacitinib citrate in patients with alopecia areata

Milène K. Crispin, Justin Ko, Brittany G. Craiglow et al. · JCI Insight · 2016 · 344 citations · Full text

Medicine, Dermatology, Pharmacology +11

Pharmacologic inhibition of JAK-STAT signaling promotes hair growth

Sivan Harel, Claire A. Higgins, Jane Cerise et al. · Science Advances · 2015 · 240 citations · Full text

Life Sciences, Dermatology, Pharmacology +15

Identification of Causal Genetic Drivers of Human Disease through Systems-Level Analysis of Regulatory Networks

James C. Chen, Mariano J. Alvarez, Flaminia Talos et al. · Cell · 2014 · 194 citations · Full text

Life Sciences, Genetics, Systems Biology +17

An Open-Label Pilot Study to Evaluate the Efficacy of Tofacitinib in Moderate to Severe Patch-Type Alopecia Areata, Totalis, and Universalis

Ali Jabbari, Freda Sansaricq, Jane Cerise et al. · Journal of Investigative Dermatology · 2018 · 184 citations · Full text

Medicine, Dermatology, Pharmacotherapy +13