Noah J. Goff

Cryo-EM of NHEJ supercomplexes provides insights into DNA repair

Amanda K. Chaplin, Steven W. Hardwick, Antonia Kefala Stavridi et al. · Molecular Cell · 2021 · 97 citations · Full text

Autophosphorylation transforms DNA-PK from protecting to processing DNA ends

Lan Liu, Xuemin Chen, Jun Li et al. · Molecular Cell · 2021 · 76 citations · Full text

Chromatin, Genome Instability, Natural Sciences +5

Two distinct long-range synaptic complexes promote different aspects of end processing prior to repair of DNA breaks by non-homologous end joining

Christopher J. Buehl, Noah J. Goff, Steven W. Hardwick et al. · Molecular Cell · 2023 · 41 citations · Full text

Chromatin, Genome Instability, End Processing +8

Catalytically inactive DNA ligase IV promotes DNA repair in living cells

Noah J. Goff, Manon Brenière, Christopher J. Buehl et al. · Nucleic Acids Research · 2022 · 26 citations · Full text

Single-molecule imaging reveals the kinetics of non-homologous end-joining in living cells

Mariia Mikhova, Noah J. Goff, Tomáš Janovič et al. · Nature Communications · 2024 · 10 citations · Full text