Katie J. Simmons

Inhibition of D-Ala:D-Ala ligase through a phosphorylated form of the antibiotic D-cycloserine

Sarah Batson, Cesira de Chiara, Vita Majce et al. · Nature Communications · 2017 · 95 citations · Full text

Pharmacy, Biochemistry, Medicinal Chemistry +15

The nature of <i>Staphylococcus aureus</i> MurA and MurZ and approaches for detection of peptidoglycan biosynthesis inhibitors

Katy L. Blake, Alex J. O’Neill, Dominique Mengin‐Lecreulx et al. · Molecular Microbiology · 2009 · 88 citations · Full text

Life Sciences, Microbiology, Molecular Biology +16

Molecular mechanism of ligand recognition by membrane transport protein, Mhp1

Katie J. Simmons, Scott M. Jackson, Florian Brueckner et al. · The EMBO Journal · 2014 · 72 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +17

Human TRPC5 structures reveal interaction of a xanthine-based TRPC1/4/5 inhibitor with a conserved lipid binding site

David J. Wright, Katie J. Simmons, Rachel M. Johnson et al. · Communications Biology · 2020 · 64 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +17

Cyclic dinucleotides bind the C-linker of HCN4 to control channel cAMP responsiveness

Marco Lolicato, Annalisa Bucchi, Cristina Arrigoni et al. · Nature Chemical Biology · 2014 · 56 citations

Life Sciences, Biochemistry, Molecular Biology +11