Single-Cell Transcriptomics Uncovers Glial Progenitor Diversity and Cell Fate Determinants during Development and Gliomagenesis

Qinjie Weng, Jincheng Wang, Jiajia Wang, +23

Cell stem cell

Cell LineageDevelopmental BiologyGliomaSingle Cell SequencingMedicine +8

Chd7 cooperates with Sox10 and regulates the onset of CNS myelination and remyelination

Danyang He, Corentine Marie, Chuntao Zhao, +16

Nature Neuroscience

Molecular NeuroscienceNeurobiology Of DiseaseCns MyelinationNeurologyNeuroscience +9

Disruption of the IL-33-ST2-AKT signaling axis impairs neurodevelopment by inhibiting microglial metabolic adaptation and phagocytic function

Danyang He, Heping Xu, Huiyuan Zhang, +17

Immunity

InflammationCytokineImmune Cell DevelopmentPhagocytic FunctionMedicine +11

lncRNA Functional Networks in Oligodendrocytes Reveal Stage-Specific Myelination Control by an lncOL1 /Suz12 Complex in the CNS

Danyang He, Jincheng Wang, Yulan Lu, +7

Neuron

NeuroregenerationMolecular NeuroscienceLncrna Functional NetworksLncol1 /Suz12 ComplexNeurological Function +9

Olig2-Dependent Reciprocal Shift in PDGF and EGF Receptor Signaling Regulates Tumor Phenotype and Mitotic Growth in Malignant Glioma

Fanghui Lu, Ying Chen, Chuntao Zhao, +20

Cancer Cell

Mitotic GrowthGliomaMedicineOlig2-dependent Reciprocal ShiftMalignant Glioma +6

Hdac3 Interaction with p300 Histone Acetyltransferase Regulates the Oligodendrocyte and Astrocyte Lineage Fate Switch

Liguo Zhang, Xuelian He, Lei Liu, +14

Developmental Cell

ChromatinDevelopmental BiologyMolecular NeuroscienceChromatin RemodelingCell Regulation +8

Coupled analysis of transcriptome and BCR mutations reveals role of OXPHOS in affinity maturation

Dianyu Chen, Yan Wang, Godhev K. Manakkat Vijay, +7

Nature Immunology

Reductive StressNatural SciencesGeneticsGene ExpressionGenomic Mechanism +8

Early developing B cells undergo negative selection by central nervous system-specific antigens in the meninges

Yan Wang, Dianyu Chen, Di Xu, +4

Immunity

Developmental BiologyAutoimmune DiseaseImmune Cell DevelopmentMedicineHumoral Response +8

Fate mapping of Spp1 expression reveals age-dependent plasticity of disease-associated microglia-like cells after brain injury

Yangning Lan, Xiaoxuan Zhang, Shaorui Liu, +13

Immunity

InflammationNeuroregenerationAlzheimer's DiseaseMedicineCell Death +12

Neuromedin U programs eosinophils to promote mucosal immunity of the small intestine

Yu Li, Shaorui Liu, Kewen Zhou, +9

Science

ImmunologyGastroenterologyImmune RegulationTranscriptome ProfilingCell Differentiation +18