Concepedia

Hitoshi Hochigai

HH

Statistics

Publications

4

Citations

104

H-Index

4

Active since

2006

Affiliations

Sumitomo Dainippon Pharma (Japan)(Current)

Hitoshi Hochigai is an author at Sumitomo Dainippon Pharma (Japan) specializing in enzyme inhibition, dipeptidyl peptidases, and medicinal chemistry.

Publications per year

2006–2014

4

Publications

4

Discovery of 3H-imidazo[4,5-c]quinolin-4(5H)-ones as potent and selective dipeptidyl peptidase IV (DPP-4) inhibitors

Yohei Ikuma, Hitoshi Hochigai, Hidenori Kimura et al. · Bioorganic & Medicinal Chemistry · 2012 · 39 citations · Full text

, , +9

Crystal structures of the catalytic domain of human stromelysin-1 (MMP-3) and collagenase-3 (MMP-13) with a hydroxamic acid inhibitor SM-25453

Tetsuya Kohno, Hitoshi Hochigai, Eiki Yamashita et al. · Biochemical and Biophysical Research Communications · 2006 · 32 citations

, , +7

Chronic administration of DSP‐7238, a novel, potent, specific and substrate‐selective DPP IV inhibitor, improves glycaemic control and <i>β</i> ‐cell damage in diabetic mice

Yoshikazu Furuta, M. Horiguchi, Eiji Sugaru et al. · Diabetes Obesity and Metabolism · 2009 · 18 citations

, , +17

Discovery of 3H-imidazo[4,5-c]quinolin-4(5H)-ones as potent and selective dipeptidyl peptidase IV (DPP-4) inhibitors: Use of a carboxylate prodrug to improve bioavailability

Yohei Ikuma, Hitoshi Hochigai, Hidenori Kimura et al. · Bioorganic & Medicinal Chemistry · 2014 · 15 citations · Full text

, , +9

1–4 of 4