Luke M. Judge

CRISPR Interference Efficiently Induces Specific and Reversible Gene Silencing in Human iPSCs

Mohammad A. Mandegar, Nathaniel Huebsch, Ekaterina B. Frolov et al. · Cell stem cell · 2016 · 529 citations · Full text

Natural Sciences, Genetics, Reversible Gene Silencing +9

Unbiased detection of CRISPR off-targets in vivo using DISCOVER-Seq

Beeke Wienert, Stacia K. Wyman, Chris D. Richardson et al. · Science · 2019 · 408 citations

Dystrophins carrying spectrin-like repeats 16 and 17 anchor nNOS to the sarcolemma and enhance exercise performance in a mouse model of muscular dystrophy

Yi Lai, Gail D. Thomas, Yongping Yue et al. · Journal of Clinical Investigation · 2009 · 371 citations · Full text

Muscle Function, Cytoskeleton, Cellular Physiology +23

Isolation of single-base genome-edited human iPS cells without antibiotic selection

Yuichiro Miyaoka, Amanda H. Chan, Luke M. Judge et al. · Nature Methods · 2014 · 331 citations · Full text

Human Cell, Genome Surgery, Molecular Technology +8

Automated Video-Based Analysis of Contractility and Calcium Flux in Human-Induced Pluripotent Stem Cell-Derived Cardiomyocytes Cultured over Different Spatial Scales

Nathaniel Huebsch, Peter Loskill, Mohammad A. Mandegar et al. · Tissue Engineering Part C Methods · 2014 · 320 citations · Full text

Tissue Engineering, Cardiac Muscle, Engineering +20