Joan Guo

Identification of potent inhibitors of Plasmodium falciparum plasmepsin II from an encoded statine combinatorial library

Carolyn DiIanni Carroll, Hitesh D. Patel, Theodore Johnson et al. · Bioorganic & Medicinal Chemistry Letters · 1998 · 68 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +16

Structure-Based Design and Synthesis of 1,3-Oxazinan-2-one Inhibitors of 11β-Hydroxysteroid Dehydrogenase Type 1

Zhenrong Xu, Colin M. Tice, Wei Zhao et al. · Journal of Medicinal Chemistry · 2011 · 40 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17

Discovery of VTP-27999, an Alkyl Amine Renin Inhibitor with Potential for Clinical Utility

Lanqi Jia, R. David Simpson, Jing Yuan et al. · ACS Medicinal Chemistry Letters · 2011 · 38 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +15

Discovery of a Novel, Orally Efficacious Liver X Receptor (LXR) β Agonist

Ya‐Jun Zheng, Linghang Zhuang, Kristi Fan et al. · Journal of Medicinal Chemistry · 2016 · 32 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +14

Pharmacological characterization of the selective 11β-hydroxysteroid dehydrogenase 1 inhibitor, BI 135585, a clinical candidate for the treatment of type 2 diabetes

Bradford S. Hamilton, Frank Himmelsbach, Herbert Nar et al. · European Journal of Pharmacology · 2014 · 29 citations

Medicine, Medicinal Chemistry, Pharmacology +12