Dominic D. G. Owens

Microhomologies are prevalent at Cas9-induced larger deletions

Dominic D. G. Owens, Adam Caulder, Vincent Frontera et al. · Nucleic Acids Research · 2019 · 145 citations · Full text

Crispr System, Larger Deletion Sizes, Natural Sciences +15

A chemical probe targeting the PWWP domain alters NSD2 nucleolar localization

David Dilworth, Ronan P. Hanley, Renato Ferreira de Freitas et al. · Nature Chemical Biology · 2021 · 102 citations · Full text

Biochemistry, Natural Sciences, Molecular Biology +7

Recruitment of FBXO22 for targeted degradation of NSD2

Yan Nie, John R. Tabor, Jianping Li et al. · Nature Chemical Biology · 2024 · 46 citations · Full text

Protein Degradation, Targeted Degradation, Drug Targeting +1

Dynamic Runx1 chromatin boundaries affect gene expression in hematopoietic development

Dominic D. G. Owens, Giorgio Anselmi, A. Marieke Oudelaar et al. · Nature Communications · 2022 · 31 citations · Full text

A chemical probe to modulate human GID4 Pro/N-degron interactions

Dominic D. G. Owens, Matthew E. R. Maitland, Aliakbar Khalili Yazdi et al. · Nature Chemical Biology · 2024 · 19 citations

Signal Transduction, Molecular Physiology, Biochemistry +9