Concepedia

Luke H. Rhym

LH

11

Publications

1.4K

Citations

11

H-Index

2015

Active since

Affiliations

Massachusetts Institute of Technology(Current)

Harvard–MIT Division of Health Sciences and Technology

Broad Institute

University of Massachusetts Chan Medical School

Harvard University

Luke H. Rhym is an author at Massachusetts Institute of Technology specializing in engineering, medicine, and biomedical engineering.

Top concepts

MedicineEngineeringNanomedicineBiomedical EngineeringBiomolecular EngineeringGene DeliveryMolecular BiologyNanoparticlesAllergyHydrogels

Publications per year

2015–2023

11

Publications

11

Structure-guided chemical modification of guide RNA enables potent non-viral in vivo genome editing

Hao Yin, Chun‐Qing Song, Sneha Suresh et al. · Nature Biotechnology · 2017 · 482 citations · Full text

Engineering, Genome Surgery, In Vivo Gene Therapy +10

Adenine base editing in an adult mouse model of tyrosinaemia

Chun‐Qing Song, Tingting Jiang, Michelle F. Richter et al. · Nature Biomedical Engineering · 2019 · 184 citations · Full text

Molecular Physiology, Mammalian Physiology, Physiology +4

Reduction of the therapeutic dose of silencing RNA by packaging it in extracellular vesicles via a pre-microRNA backbone

Ryan Reshke, James A. Taylor, Alexandre Savard et al. · Nature Biomedical Engineering · 2020 · 151 citations · Full text

Extracellular Vesicles, Therapeutic Dose, Natural Sciences +10

Enhancing the immunogenicity of lipid-nanoparticle mRNA vaccines by adjuvanting the ionizable lipid and the mRNA

Bowen Li, Allen Yujie Jiang, Idris Raji et al. · Nature Biomedical Engineering · 2023 · 129 citations

Vaccination, Nanomedicine, Cross-protection +11

Customizable Lipid Nanoparticle Materials for the Delivery of siRNAs and mRNAs

Owen S. Fenton, Kevin Kauffman, Rebecca L. McClellan et al. · Angewandte Chemie International Edition · 2018 · 119 citations · Full text

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