Lactate supports a metabolic-epigenetic link in macrophage polarization

Jordan T. Noe, Beatriz E. Rendon, Anne E. Geller, +18

Science Advances

FAM83B mediates EGFR- and RAS-driven oncogenic transformation

Rocky Cipriano, James Graham, Kristy Miskimen, +6

Journal of Clinical Investigation

Aberrant RegulationCraf Membrane LocalizationSignaling PathwayMedicineRas-driven Oncogenic Transformation +9

Brain glycogen serves as a critical glucosamine cache required for protein glycosylation

Ramon C. Sun, Lyndsay E.A. Young, Ronald C. Bruntz, +30

Cell Metabolism

Protein GlycosylationBiochemistryMedicineNatural SciencesGlycobiology +7

APOE alters glucose flux through central carbon pathways in astrocytes

Holden C. Williams, Brandon C. Farmer, Margaret A. Piron, +5

Neurobiology of Disease

De novo synthesis of serine and glycine fuels purine nucleotide biosynthesis in human lung cancer tissues

Teresa W.‐M. Fan, Ronald C. Bruntz, Ye Yang, +11

Journal of Biological Chemistry

Phospholipase D2 Mediates Survival Signaling through Direct Regulation of Akt in Glioblastoma Cells

Ronald C. Bruntz, Harry E. Taylor, Craig W. Lindsley, +1

Journal of Biological Chemistry

Direct RegulationSignal TransductionSignaling PathwayGliomaReceptor Tyrosine Kinase +9

Spatial metabolomics reveals glycogen as an actionable target for pulmonary fibrosis

Lindsey R. Conroy, Harrison A. Clarke, Derek B. Allison, +19

Nature Communications

Hyperactivation of EGFR and downstream effector phospholipase D1 by oncogenic FAM83B

Rocky Cipriano, Benjamin L. Bryson, Kristy Miskimen, +7

Oncogene

Signal TransductionSignaling PathwayCell RegulationReceptor Tyrosine KinaseProtein Phosphorylation +7

Individual differences in response to novelty predict prefrontal cortex dopamine transporter function and cell surface expression

Jun Zhu, Michael T. Bardo, Ronald C. Bruntz, +2

European Journal of Neuroscience

NeuropsychologyBrain FunctionBehavioral AddictionAffective NeuroscienceIndividual Differences +21

Quantitative profiling of carbonyl metabolites directly in crude biological extracts using chemoselective tagging and nanoESI-FTMS

Pan Deng, Richard M. Higashi, Andrew N. Lane, +6

The Analyst