Sheila Higginbotham

Molecular origin of cancer: Catechol estrogen-3,4-quinones as endogenous tumor initiators

Ercole L. Cavalieri, Douglas E. Stack, Prabhakar D. Devanesan et al. · Proceedings of the National Academy of Sciences · 1997 · 730 citations

Medicine, Molecular Biology, Oncology +17

Comparative dose—response tumorigenicity studies of dibenzo[<i>a,l</i>]pyrene versus 7, 12-dimethylbenz[<i>a</i>]anthracene, benzo[<i>a</i> and two dibenzo[<i>a,l</i>]pyrene dihydrodiols in mouse skin and rat mammary gland

Ercole L. Cavalieri, Sheila Higginbotham, N. V. S. Ramakrishna et al. · Carcinogenesis · 1991 · 246 citations

Pharmacy, Oncology, Toxicology +6

Catechol ortho-quinones: the electrophilic compounds that form depurinating DNA adducts and could initiate cancer and other diseases

Ercole L. Cavalieri, Kaiming Li, Narayanan Balu et al. · Carcinogenesis · 2002 · 225 citations

Pharmacy, Biochemistry, Toxicology +15

Tumor-initiating activity and carcinogenicity of dibenzo[<i>a,l</i>]pyrene versus 7, 12-dimethylbenz[<i>a</i>]anthracene and benzo[<i>a</i>]pyrene at low doses in mouse skin

Sheila Higginbotham, N. V. S. Ramakrishna, Sonny L. Johansson et al. · Carcinogenesis · 1993 · 199 citations

Pharmacy, Toxicology, Comparative Toxicology +13

Evidence that a burst of DNA depurination in SENCAR mouse skin induces error-prone repair and forms mutations in the H-ras gene

Dhrubajyoti Chakravarti, Paula C. Mailander, Kai-Ming Li et al. · Oncogene · 2001 · 172 citations

Life Sciences, Genetics, Molecular Biology +17