James J. Champoux

Crystal Structures of Human Topoisomerase I in Covalent and Noncovalent Complexes with DNA

Matthew R. Redinbo, Lance Stewart, Peter Kühn et al. · Science · 1998 · 874 citations

A Model for the Mechanism of Human Topoisomerase I

Lance Stewart, Matthew R. Redinbo, Xiayang Qiu et al. · Science · 1998 · 698 citations

DNA topoisomerase I is involved in both repression and activation of transcription

Alejandro Merino, Knut Madden, William S. Lane et al. · Nature · 1993 · 379 citations

Chromatin, Transcriptional Regulation, Chromatin Remodeling +13

An Activity from Mammalian Cells That Untwists Superhelical DNA—A Possible Swivel For DNA Replication

James J. Champoux, Renato Dulbecco · Proceedings of the National Academy of Sciences · 1972 · 337 citations · Full text

Chromatin, Genome Instability, Dna Nanotechnology +15

The tyrosyl-DNA phosphodiesterase Tdp1 is a member of the phospholipase D superfamily

Heidrun Interthal, Jeffrey J. Pouliot, James J. Champoux · Proceedings of the National Academy of Sciences · 2001 · 284 citations · Full text

Proteinlipid Interaction, Protein Function, Signal Transduction +15