Els Kievit

Superiority of yeast over bacterial cytosine deaminase for enzyme/prodrug gene therapy in colon cancer xenografts.

Els Kievit, Eric M. Bershad, Enoch Ng et al. · PubMed · 1999 · 177 citations

Enzyme/prodrug Gene Therapy, Tumor Biology, Enzyme/prodrug Strategy +14

Noninvasive quantitation of cytosine deaminase transgene expression in human tumor xenografts with <i>in vivo</i> magnetic resonance spectroscopy

Lauren D. Stegman, Alnawaz Rehemtulla, Bradley J. Beattie et al. · Proceedings of the National Academy of Sciences · 1999 · 150 citations · Full text

Engineering, Transgene Expression, Cancer Biology +16

Zirconium-labeled monoclonal antibodies and their distribution in tumor-bearing nude mice.

W.E. Meijs, Hidde J. Haisma, Rob P. Klok et al. · PubMed · 1997 · 92 citations

Yeast cytosine deaminase improves radiosensitization and bystander effect by 5-fluorocytosine of human colorectal cancer xenografts.

Els Kievit, Mukesh K. Nyati, Emily Ng et al. · PubMed · 2000 · 86 citations

Tumor Biology, Bystander Effect, Cytosine Deaminase +15

The potential of 5-fluorocytosine/cytosine deaminase enzyme prodrug gene therapy in an intrahepatic colon cancer model

MK Nyati, Zvi Symon, Els Kievit et al. · Gene Therapy · 2002 · 59 citations

Medicine, Pharmacology, Colorectal Cancer +6