Human-specific gene <i>ARHGAP11B</i> promotes basal progenitor amplification and neocortex expansion

Marta Florio, Mareike Albert, Elena Taverna, +17

Science

GeneticsGenomic MechanismEpigeneticsHuman NeocortexEpendyma +17

Evolution and cell-type specificity of human-specific genes preferentially expressed in progenitors of fetal neocortex

Marta Florio, Michael Heide, Anneline Pinson, +6

eLife

Jarid1b targets genes regulating development and is involved in neural differentiation

Sandra U. Schmitz, Mareike Albert, Martina Malatesta, +6

The EMBO Journal

Neural DifferentiationMolecular NeuroscienceDevelopmental BiologyDevelopmental GeneticsGenetics +9

The Histone Demethylase Jarid1b Ensures Faithful Mouse Development by Protecting Developmental Genes from Aberrant H3K4me3

Mareike Albert, Sandra U. Schmitz, Susanne M. Kooistra, +6

PLoS Genetics

Histone ModificationsDevelopmental GenesEpigenetic ChangeGeneticsMolecular Genetics +19

Paternal heterochromatin formation in human embryos is H3K9/HP1 directed and primed by sperm-derived histone modifications

C. van de Werken, Godfried W. van der Heijden, Cindy Eleveld, +6

Nature Communications

Human-specific ARHGAP11B induces hallmarks of neocortical expansion in developing ferret neocortex

Nereo Kalebic, Carlotta Gilardi, Mareike Albert, +5

eLife

Epigenome profiling and editing of neocortical progenitor cells during development

Mareike Albert, Nereo Kalebic, Marta Florio, +5

The EMBO Journal

ChromatinEpigenome ProfilingCell LineageDevelopmental BiologyBrain Development +8

Polycomb proteins control proliferation and transformation independently of cell cycle checkpoints by regulating DNA replication

Andrea Piunti, Alessandra Rossi, Aurora Cerutti, +12

Nature Communications

Pcg InhibitionMolecular BiologyCell CycleCancer BiologyEpigenetics +17

Cbx2 Targets PRC1 to Constitutive Heterochromatin in Mouse Zygotes in a Parent-of-Origin-Dependent Manner

Mathieu Tardat, Mareike Albert, Rico Kunzmann, +7

Molecular Cell

ChromatinChromatin StructureCell DivisionChromatin RemodelingConstitutive Heterochromatin +11

RSV-Induced H3K4 Demethylase KDM5B Leads to Regulation of Dendritic Cell-Derived Innate Cytokines and Exacerbates Pathogenesis In Vivo

Catherine Ptaschinski, Sumanta Mukherjee, Martin L. Moore, +4

PLoS Pathogens

Inflammatory Lung DiseaseInnate Immune SystemImmunologyImmune RegulationImmunologic Mechanism +21