Hiroki Tsukamoto

Gut microbiome-derived phenyl sulfate contributes to albuminuria in diabetic kidney disease

Kôichi Kikuchi, Daisuke Saigusa, Yoshitomi Kanemitsu et al. · Nature Communications · 2019 · 297 citations · Full text

Medicine, Biochemistry, Nephrology +17

Evaluation of the impact of gut microbiota on uremic solute accumulation by a CE-TOFMS–based metabolomics approach

Eikan Mishima, Shinji Fukuda, Chikahisa Mukawa et al. · Kidney International · 2017 · 243 citations · Full text

Life Sciences, Biochemistry, Microbiology +17

Lipopolysaccharide (LPS)-binding protein stimulates CD14-dependent Toll-like receptor 4 internalization and LPS-induced TBK1–IKKϵ–IRF3 axis activation

Hiroki Tsukamoto, Shino Takeuchi, Kanae Kubota et al. · Journal of Biological Chemistry · 2018 · 217 citations · Full text

Life Sciences, Immunology, Microbiology +17

Lipopolysaccharide-binding protein-mediated Toll-like receptor 4 dimerization enables rapid signal transduction against lipopolysaccharide stimulation on membrane-associated CD14-expressing cells

Hiroki Tsukamoto, Kenji Fukudome, Sonshin Takao et al. · International Immunology · 2010 · 105 citations

Life Sciences, Immunology, Molecular Biology +17

Canagliflozin reduces plasma uremic toxins and alters the intestinal microbiota composition in a chronic kidney disease mouse model

Eikan Mishima, Shinji Fukuda, Yoshitomi Kanemitsu et al. · American Journal of Physiology-Renal Physiology · 2017 · 105 citations · Full text

Medicine, Nephrology, Pharmacology +17