Lei Lv

Acetylation Targets the M2 Isoform of Pyruvate Kinase for Degradation through Chaperone-Mediated Autophagy and Promotes Tumor Growth

Lei Lv, Li Dong, Di Zhao et al. · Molecular Cell · 2011 · 586 citations · Full text

Cell Autophagy, Mitophagy, Biochemistry +11

Discovery of Zanubrutinib (BGB-3111), a Novel, Potent, and Selective Covalent Inhibitor of Bruton’s Tyrosine Kinase

Yunhang Guo, Ye Liu, Nan Hu et al. · Journal of Medicinal Chemistry · 2019 · 332 citations · Full text

Mitogenic and Oncogenic Stimulation of K433 Acetylation Promotes PKM2 Protein Kinase Activity and Nuclear Localization

Lei Lv, Yan-Ping Xu, Di Zhao et al. · Molecular Cell · 2013 · 319 citations · Full text

Signal Transduction, Signaling Pathway, Cell Regulation +12

WT1 Recruits TET2 to Regulate Its Target Gene Expression and Suppress Leukemia Cell Proliferation

Yiping Wang, Mengtao Xiao, Xiufei Chen et al. · Molecular Cell · 2015 · 298 citations · Full text

Cell Regulation, Medicine, Wt1 Recruits Tet2 +10

Tumor suppressor TET2 promotes cancer immunity and immunotherapy efficacy

Yanping Xu, Lei Lv, Ying Liu et al. · Journal of Clinical Investigation · 2019 · 223 citations · Full text

Pd-l1 Genes, Immunology, Immune Regulation +16