Chao-Chien Chang

Andrographolide stimulates p38 mitogen-activated protein kinase–nuclear factor erythroid-2-related factor 2–heme oxygenase 1 signaling in primary cerebral endothelial cells for definite protection against ischemic stroke in rats

Ting‐Lin Yen, Ray‐Jade Chen, Thanasekaran Jayakumar et al. · Translational research · 2015 · 81 citations

Thrombosis, Definite Protection, Cerebral Vascular Regulation +15

Platelet protease-activated receptor (PAR)4, but not PAR1, associated with neutral sphingomyelinase responsible for thrombin-stimulated ceramide-NF- B signaling in human platelets

Wen‐Fang Chen, J.-J. Lee, Chao-Chien Chang et al. · Haematologica · 2012 · 53 citations · Full text

Neutral Sphingomyelinase, Immunology, P38 Mapk +21

Hinokitiol, a tropolone derivative, inhibits mouse melanoma (B16-F10) cell migration and in vivo tumor formation

Chien‐Hsun Huang, Shing-Hwa Lu, Chao-Chien Chang et al. · European Journal of Pharmacology · 2014 · 50 citations

Tumor Biology, Vivo Tumor Formation, Tropolone Derivative +10

Platelet autophagic machinery involved in thrombosis through a novel linkage of AMPK-MTOR to sphingolipid metabolism

Tzu-Yin Lee, Wan‐Jung Lu, Chun A. Changou et al. · Autophagy · 2021 · 46 citations · Full text

Brazilin Ameliorates High Glucose-Induced Vascular Inflammation via Inhibiting ROS and CAMs Production in Human Umbilical Vein Endothelial Cells

Thanasekaran Jayakumar, Chao-Chien Chang, Shoei-Loong Lin · BioMed Research International · 2014 · 39 citations · Full text